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Table 2 The association of Indiana’s opioid prescription emergency rules to daily Morphine Equivalent Dose (MED) per patient of different opioids dispensed in Indiana

From: The effects of state rules on opioid prescribing in Indiana

Drug Name

Impact of policy

Pre-policy Time Trend

Post-policy time trend

All opioids

−3.17***

−0.0021***

−0.0044***

hydrocodone

−3.68***

−0.0038***

−0.0048***

oxycodone

−2.03***

−0.0015***

−0.0133***

morphine

−0.03

−.0101***

−0.0185***

methadone

−6.19***

−.0026***

−0.0333***

fentanyl

−1.15

−.0080***

−0.0169***

oxymorphone

−3.11*

−.0245***

−0.0142*

buprenorphine

−.47

−.0022***

−0.0209***

hydromorphone

−3.54**

.0005

−0.0143*

  1. Coefficients and t-statistics from Interrupted Time Series Analysis. *p ≤ 0.10, **p ≤ 0.05, ***p ≤ 0.01