From: Real-world costs of autosomal dominant polycystic kidney disease in the Nordics
Costs in EUR, mean (95% CI) | CKD 1–3 (n = 64) | CKD 4–5 (n = 55) | Dialysis (n = 61) | Transplant (n = 63) | P value |
---|---|---|---|---|---|
Direct costs | 3676 (2223–6190) | 5883 (4588–7701) | 64,811 (60,460–70,417) | 20,305 (16,228–25,166) | <0.0001 |
Hospitalisations | 507 (172–1125) | 1309 (515–2611) | 5455 (3666–7670) | 2557 (1283–4299) | <0.0001 |
Outpatient care visits | 1159 (843–1569) | 2057 (1606–2871) | 3203 (2329–4230) | 3197 (2502–4155) | <0.0001 |
Primary care visits | 237 (117–403) | 414 (84–1097) | 174 (50–548) | 121 (48–265) | .5094 |
Surgical procedures | 249 (15–794) | 511 (154–1098) | 2562 (1211–5119) | 1009 (435–1956) | <0.0001 |
Diagnostic tests | 191 (125–263) | 237(166–321) | 659 (511–843) | 354 (251–496) | <0.0001 |
Home care/medical assistance | 1048 (4–3049) | 74 (5–204) | 1093 (384–2044) | 260 (28–837) | .0002 |
Routine dialysis care | – | – | 42,900 (40,609–44,964) | 1398 (368–2810) | <0.0001 |
Haemodialysis transportation | – | – | 4090 (3184–5080) | 13 (0–25) | <0.0001 |
Drug use | 284 (175–419) | 1281 (1008–1600) | 4675 (4040–5512) | 11,396 (9404–13,944) | <0.0001 |
Antihypertensives | 68 (54–86) | 113 (95–132) | 73 (60–86) | 96 (78–117) | .0020 |
Phosphate binders | – | 225 (103–362) | 1266 (1006–1554) | 65 (15–148) | <0.0001 |
ESAs | 4 (0–15) | 204 (78–361) | 1413 (1181–1611) | 209 (89–370) | <0.0001 |
Analgesics for kidney pain | 3 (1–7) | 14 (5–30) | 12 (4–25) | 4 (0–12) | .1329 |
Vitamin D analogues | 198 (93–335) | 689 (516–878) | 1318 (1207–1407) | 455 (310–620) | <0.0001 |
Immunosupressants | – | – | 440 (26–1076) | 10,469 (8516–12,955) | <0.0001 |
Other drugs | 10 (3–27) | 36 (17–61) | 154 (126–183) | 99 (48–171) | <0.0001 |
Indirect costs | 4863 (2986–7132) | 9904 (6738–13,319) | 7674 (5195–10,042) | 7585 (5125–10,494) | .0925 |
Productivity loss | 4835 (2959–7104) | 9667 (6586–13,018) | 6783 (4586–8815) | 7488 (5058–10,382) | .2742 |
Informal care | 28 (0–83) | 237 (79–475) | 891 (353–1807) | 97 (38–176) | <0.0001 |
Total costs | 8539 (6042–11,631) | 15,787 (12,006–20,008) | 72,486 (67,053–79,025) | 27,890 (22,669–33,722) | <0.0001 |