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Table 2 Characteristics of the included studies

From: Cost-effectiveness of lung cancer screening and treatment methods: a systematic review of systematic reviews

Reference

Aim of study

No. of all publications included

Meta-Analysis

Time Horizon covered

Quality assessment tool

Screening or treatment

Clegg, Scott et al. 2001 [84]

Examines the cost-effectiveness of four of the newer drugs –vinorelbine, gemcitabine, paclitaxel and docetaxel used for treating the most common type of lung cancer (non-small-cell lung cancer).

16

NO

1995–2000

appended appraisal questions

treatment

Lange, Prenzler et al. 2014 [85]

review and assess the economic evidence of treatments with targeted agents in advanced: Non-small cell lung cancer

19

NO

2000–2013

The Quality of Health Economic Studies (QHES)

treatment

Bongers, Coupe et al. 2012 [86]

comparing the new agents docetaxel, paclitaxel, vinorelbine, gemcitabine and pemetrexed, and the targeted therapies erlotinib and gefitinib with one another

10

NO

2001–2010

British Medical Journal (BMJ) 35-item checklist

treatment

Raymakers, Mayo et al. 2016 [87]

cost-effectiveness of lung cancer screening using low-dose computed tomography (LDCT)

13

NO

2000–2014

Drummond checklist

Screening

Maher, Miake-Lye et al. 2012 [88]

cost and cost-effectiveness of the different approaches in Treatment of Metastatic Non-Small Cell Lung Cancer

22

NO

1996–2010

-

treatment

Brown, Pilkington et al. 2013[89]

Cost-effectiveness of first-line chemotherapy for patients with advanced and/or metastatic NSCLC.

6

NO

1980–2010

35-item list described by Drummond and Jefferson

treatment

Cao, Rodrigues et al. 2012[90]

describing cost-effectiveness of positron-emission tomography(PET) in staging of non–small-cell lung cancer (NSCLC) and management of solitary pulmonary nodules (SPN)

18

NO

1950–2010

Quality of Health Economic Studies (QHES)

Screening

Black, Bagust et al. 2006 [58]

examine the cost-effectiveness of screening for lung cancer using computed tomography (CT)

6

NO

1994–2005

checklist developed by Drummond and colleagues

Screening