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Table 4 QMs Attainment at Baseline, Week 52 and Week 104 in the overall population

From: A post-hoc analysis of the comparative efficacy of canagliflozin and glimepiride in the attainment of type 2 diabetes-related quality measures

  

CANA 100 mg (N = 483)

CANA 300 mg (N = 485)

GLIM (N = 482)

Measure

 

%

Difference vs. GLIM, % (95 % Cl)

%

Difference vs. GLIM, % (95 % Cl)

%

A1C

 <7.0 %

Baseline

12.2

 

14.6

 

13.5

52 weeks

53.6

−2.3 (−8.8; 4.3)

60.1

4.3 (−2.2; 10.8)

55.7

104 weeks

42.5

−1.4 (−7.9; 5.1)

50.2

6.3 (−0.2; 12.9)

43.9

 <8.0 % (good control)

Baseline

61.1

 

59.9

 

60.1

52 weeks

88.7

4.3 (−0.2; 8.9)

89.2

4.9 (0.4; 9.4)

84.4

104 weeks

83.9

7.9 (2.7; 13.2)

84.6

8.6 (3.4; 13.9)

75.9

 >9.0 % (poor control)

Baseline

6.5

 

7.2

 

7.2

52 weeks

1.9

−2.1 (−4.5; 0.2)

1.7

−2.3 (−4.7; −0.0)

4.0

104 weeks

2.5

−2.8 (−5.4; −0.1)

1.9

−3.4 (−5.9; −0.8)

5.3

Blood pressure

 <140/90 mm Hg

Baseline

74.1

 

74.2

 

75.0

52 weeks

83.7

10.6 (5.2; 16.0)

85.4

12.3 (7.0; 17.6)

73.1

104 weeks

79.6

5.4 (−0.1; 10.9)

84.2

10.0 (4.7; 15.3)

74.2

Body mass index and body weight

 ≤30 kg/m2

Baseline

44.5

 

46.3

 

48.1

52 weeks

57.4

10.5 (4.0; 17.1)

55.6

8.8 (2.2; 15.3)

46.9

104 weeks

57.3

10.2 (3.7; 16.7)

54.8

7.7 (1.2; 14.2)

47.1

 ≥25 kg/m2 but ≥10 lb (4.5 kg) weight loss from baseline

Baseline

     

52 weeks

27.1

20.2 (15.4; 25.0)

34.6

27.7 (22.6; 32.7)

6.9

104 weeks

27.9

20.0 (15.1; 24.9)

34.6

26.6 (21.5; 31.7)

7.9

  1. A1C glycated hemoglobin, CANA canagliflozin, GLIM glimepiride, 95 % Cl 95 % confidence interval