Table 1 Study variables
Domain | Variables or Questionnaires | Description | Assessment |
|---|---|---|---|
Socio-demographic | Date of birth, health centre, sex | Baseline | |
Control Data | Date of interview, person interviewed | Baseline | |
Frailty | Modified Fried frailty criteria | Unintentional weight loss, low level of physical activity, low energy/tiredness, muscle weakness, slow movements | Baseline |
Tilburg Frailty Index | 15 items, 3 domains (physical, psychological and social) | Baseline | |
KoS Model | Age + Polypharmacy + Timed Up-and-Go test | Baseline | |
Gérontopôle Frailty Screening Tool | 6 items + Clinical judgement | Baseline | |
Health-related lifestyle | Physical activity - Short Physical Performance Battery | 3 tests: balance, walking speed and getting up and sitting down from a chair 5 times | Baseline |
Tobacco use | 3 items | Baseline | |
Malnutrition screening - Mini Nutritional Assessment | 18 items | Baseline | |
Health Status | Self-perceived health | 1 item | Baseline |
Healt-related quality of life - EuroQol 5D | 5 items + 0–100 visual analogue scale | Baseline | |
Cognitive state - Mini-cog test | 14 items, 5 domains: orientation, attention, concentration, calculation, memory, language and construction | Baseline | |
Geriatric syndromes | Sight, hearing and falls | Baseline | |
Comorbidity (I) | Review of 10 diseases in clinical record | Baseline | |
Comorbidity (II): Cumulative Illness Rating Scale | Review of 19 diseases in clinical record | Baseline | |
Comorbidity (III): Charlson Comorbidity Index | Review of 13 diseases in clinical record | Baseline | |
Drug use | Assessment of 5 therapeutic groups of drugs | Baseline | |
Functional capacity | Basic activities of daily living - Barthel Index | 10 items | Baseline, 1 year, 2 years |
Instrumental activities of daily living - Lawton & Brody scale | 8 items | Baseline | |
Biomarkers | 2 markers | SOX2 and p16lNK4a | Baseline |
Health resources use | Use of Primary and Specialty Healthcare Resources | Primary Care, ER, Hospitalization | 1 year, 2 years |
Adverse events | Loss of autonomy; Death | 1 year, 2 years | |