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Table 1 Identifying major IHD or cerebrovascular hospitalizations

From: Identification of major cardiovascular events in patients with diabetes using primary care data

GP codesa/drug (at least 1 prescription) TP FP TN FN Sens (95 % CI) Spec (95 % CI) PPV (95 % CI) NPV (95 % CI)
IHD/cerebrovascular hospitalizations
 GP codes 312 567 15934 417 43 (39–46) 97 (96–97) 35 (32–39) 97 (97–98)
 GP codes/nitrates 498 1602 14899 231 68 (65–72) 90 (90–91) 24 (22–26) 98 (98–99)
 GP codes/nitrates/platelet aggregation inhibitors 672 5123 11378 57 92 (90–94) 69 (68–70) 12 (11–12) 100 (99–100)
 GP codes/nitrates/platelet aggregation inhibitors/vitamin k antagonists 685 6297 10204 44 94 (92–96) 62 (61–63) 10 (9–11) 100 (99–100)
IHD hospitalizations
 GP codes 212 431 16240 347 38 (34–42) 97 (97–98) 33 (29–37) 98 (98–98)
 GP codes/nitrates 391 1499 15172 168 70 (66–74) 91 (91–91) 21 (19–23) 99 (99–99)
 GP codes/nitrates/platelet aggregation inhibitors 520 5217 11454 39 93 (91–95) 69 (68–69) 9 (8–10) 100 (100–100)
 GP codes/nitrates/platelet aggregation inhibitors/vitamin k antagonists 529 6421 10250 30 95 (92–96) 61 (61–62) 8 (7–8) 100 (100–100)
Cerebrovascular hospitalizations
 GP codes 105 172 16874 79 57 (50–64) 99 (99–99) 38 (32–44) 100 (99–100)
 GP codes/platelet aggregation inhibitors 161 5162 11884 23 88 (82–92) 70 (69–70) 3 (3–4) 100 (100–100)
 GP codes/platelet aggregation inhibitors/vitamin k antagonists 168 6603 10443 16 91 (86–95) 61 (61–62) 2 (2–3) 100 (100–100)
  1. Abbreviations: IHD ischaemic heart disease, GP general practitioner, TP true positive, FP false positive, TN true negative, FN false negative, Sens sensitivity, Spec specificity, PPV positive predictive value, NPV negative predictive value
  2. aGP codes are the following primary care diagnoses: angina pectoris (ICPC code K74), myocardial infarction (ICPC code K75), other or chronic ischemic heart disease (ICPC code K76), transient cerebral ischemia (ICPC code K89), stroke or cerebrovascular accident (ICPC code K90), coronary artery bypass grafting or percutaneous transluminal coronary angioplasty