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Table 3 Associations of TM6SF2 rs58542926 with health utilization and hospitalization (n = 3759)

From: Association of PNPLA3 rs738409 and TM6SF2 rs58542926 with health services utilization in a population-based study

Reference: TM6SF2 rs58542926 CC Effect on annual outpatient visits, % Bootstrap (95 %-CI),a Hospitalization, OR Bootstrap (95 %-CI) Effect on annual inpatient days, % Bootstrap (95 %-CI),a
Model 1 (age, sex, school education, income, alcohol intake, smoking status, eGFR)    
 CT +53.04 (+18.33, +115.29)* 1.93 (0.67, 5.03) +85.33 (+18.94, +188.78)*
 TT +67.56 (+28.28, +134.59)* 1.81 (0.59, 5.08) +123.74 (+33.14, +275.97)*
Model 2: model 1 + Functional Comorbidity Index    
 CT +57.82 (+23.62, +113.43)* 1.96 (0.68, 5.56) +94.01 (37.83, 173.1)*
 TT +69.79 (+31.60, 145.43)* 1.82 (0.72, 5.75) +133.49 (51.86, 259.0)*
Model 3: Model 2 + hepatic steatosis    
 CT +56.54 (+15.03, +110.21)* 1.93 (0.78, 5.44) +93.36 (+35.99, +174.93)*
 TT +69.28 (+24.58, +130.01)* 1.80 (0.68, 5.10) +132.83 (+51.83, +257.1)*
Model 4: Model 2 + ALT    
 CT +56.51 (+19.96, +112.33)* 1.91 (0.65, 4.98) +91.50 (+40.32, +161.36)*
 TT +69.65 (+31.38, 136.92)* 1.79 (0.63, 5.04) +131.08 (+53.60, 247.63)*
Model 5: Model 2 + ferritin    
 CT +55.75 (+21.37, +106.99)* 1.83 (0.63, 5.38) +94.00 (+37.65, +173.43)*
 TT +69.09 (+31.92, +134.08)* 1.73 (0.56, 4.98) +133.47 (+52.00, +259.61)*
Model 6: Model 1 + metabolic syndrome    
 CT +45.21 (+7.26, +107.45)** 1.81 (0.65, 5.34) +74.58 (+13.38, +168.79)**
 TT +60.48 (+14.54, 124.9)* 1.73 (0.68, 5.63) +114.92 (+30.05, +255.17)*
Model 7: Model 1 + waist circumference    
 CT +49.27 (7.63, +95.57)* 1.92 (0.80, 5.12) +90.50 (+32.88, +73.10)*
 TT +63.27 (+23.38, +138.34)* 1.79 (0.70, 4.71) +131.9 (+47.56, 264.6)*
Model 8: Model 1 + BMI    
 CT +50.28 (+12.46, 106.67)* 1.92 (0.58, 5.49) +92.70 (+27.32, 191.65)*
 TT +64.73 (+23.39, +119.28)* 1.80 (0.55, 5.21) +133.3 (+41.87, 283.35)*
Model 9: Model 1 + triglycerides    
 CT +50.08 (+15.38, +195.16)* 1.89 (0.68, 5.61) +83.47 (+16.35, +189.29)*
 TT +65.92 (+23.72, +120.61)* 1.79 (0.62, 5.14) +119.17 (+29.87, 269.89)*
Model 10: Model 1 + HDL cholesterol    
 CT +50.69 (+15.98, +238.0)* 1.89 (0.69, 5.14) +77.12 (+11.73, +180.78)**
 TT +66.26 (+26.23, +158.59)* 1.75 (0.64, 5.04) +116.1 (+27.42, +266.50)*
Model 11: Model 1 + systolic blood pressure    
 CT +53.16 (+22.27, +141.1)* 1.93 (0.60, 5.09) +84.63 (+18.88, +186.75)*
 TT +66.64 (+30.17, 167.93)* 1.77 (0.51, 4.73) +124.11 (+33.36, +276.62)*
Model 12: Model 1 + serum glucose    
 CT +50.51 (+13.57, +105.38)* 1.91 (0.64, 5.50) +82.57 (+17.68, 183.2)*
 TT +63.36 (+21.72, 116.9)* 1.81 (0.58, 5.47) +121.82 (+32.44, 271.50)*
Model 13: Model 1 + hbA1c    
 CT +53.38 (+21.00, +109.69)* 1.94 (0.82, 5.74) +85.09 (+18.75, +188.49)*
 TT +67.02 (+29.44, 23.17)* 1.82 (0.72, 5.52) +122.18 (+32.83, 275.01)*
  1. Model 1 included age, sex, school education, income, alcohol intake, smoking status, eGFR
  2. Bias-corrected Bootstrap confidence intervals
  3. CI confidence interval
  4. a Percent change compared to the ‘CC-genotype’ group
  5. *p-value < 0.01
  6. **p-value < 0.05