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Table 6 Costs of chemotherapy for advanced colorectal cancer in the world (USD, monthly)

From: Real-world cost analysis of chemotherapy for colorectal cancer in Japan: detailed costs of various regimens during the entire course of chemotherapy

 

Oxaliplatin-based regimens

Irinotecan-based regimens

Regimens including molecular targeted agents

Japan (Present study)

FOLFOX: 4,141

IRIS: 2,217

FOLFOX + Bev: 7,353

FOLFIRI (2nd line): 1,574

FOLFIRI + Bev or Cet: 6,777

Japan (Miyazaki14)

FOLFOX: 4,151

FOLFIRI: 2,398

 

Japan (Shiroiwa15)

FOLFOX: 4,554

FOLFIRI (2nd line): 2,376

FOLFOX + Bev: 7,722

XELOX: 3,564

IFL + Bev: 4,950

XELOX + Bev: 6,831

Japan (Ajima16)

FOLFOX: 5,352

FOLFIRI: 3,743

 

US (Mullins23)

FOLFOX: 60,179 (per patient)

FOLFIRI: 44,087 (per patient)

 

US (Tumeh24)

FOLFOX: 29,865 (per patient)

FOLFIRI: 24,551 (per patient)

 

US (Chu30)

FOLFOX: 14,300

  

XELOX: 11,473

UK (NICE:HTA200125)

FOLFOX: 5,718

FOLFIRI: 5,975

 

UK (NICE:HTA200826)

FOLFOX: 22,734 (per patient)

FOLFIRI: 23,017 (per patient)

 

UK (Tappenden27)

 

IFL: 40,998 (per patient)

IFL + Bev: 74,379 (per patient)

France (Perrocheau32)

FOLFOX: 23,597 (per patient)

  

XELOX: 17,695 (per patient)

Koria (Lee28)

 

FOLFIRI: 1,597

Bev: 5,150

UK (Ward31)

5-FU/LV (Mayo): 2,065

Capecitabine: 1,225

UFT/LV: 1,944

  1. IFL irinotecan plus fluorouracil and leucovorin; 5-FU 5-fluorouracil; LV leucovorin; UFT tegafur and uracil combination
  2. Rate: 1 USD (US Dollar) = 101 JPY, 0.58 GBP (British Pound), 0.73 EUR (Euro) (2014/7/9)