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Table 1 Baseline characteristics of the study cohort stratified by time of ICU discharge

From: Association Between Nighttime Discharge from the Intensive Care Unit and Hospital Mortality: A Multi-Center Retrospective Cohort Study

Characteristics

Total

Nighttime discharges

Daytime discharges

P value

n: 19,622

n = 3,505 (17.9 %)

n = 16,117 (82.1 %)

Male sex, n (%)

11,357 (57.9)

1,986 (56.7)

9,371 (58.1)

0.11

Age (years) (mean [SD])

57.5 (18.0)

57.2 (17.9)

57.5 (18.0)

0.30

Apache II score (mean [SD])

19.4 (7.5)

20.1 (7.6)

19.3 (7.4)

<0.001

Medical admission, n (%)

13,018 (66.3)

2,596 (74.1)

10,422 (64.7)

<0.001

Post-operative, n (%)

6,604 (33.7)

909 (25.9)

5,695 (35.3)

<0.001

Comorbid illness, n (%)

 None

15,180 (77.4)

2,662 (76.0)

12,518 (77.7)

0.027

 One

3,927 (20.0)

730 (20.8)

3,197 (19.8)

0.19

 Two or more

515 (2.6)

113 (3.2)

402 (2.5)

0.014

Comorbid condition, n (%)

 Hepatic failure

873 (4.5)

150 (4.3)

723 (4.5)

0.59

 Immunosuppression

981 (5.0)

207 (5.9)

774 (4.8)

0.007

 Chronic lung disease

1,355 (6.9)

228 (6.5)

1,127 (7.0)

0.30

 Chronic renal failure

613 (3.1)

159 (4.5)

454 (2.8)

<0.001

 Hematologic cancer

314 (1.6)

63 (1.8)

251 (1.6)

0.31

 Metastatic cancer

465 (2.4)

83 (2.4)

382 (2.4)

0.99

 Congestive heart failure

293 (1.5)

53 (1.5)

240 (1.5)

0.92

 AIDS

82 (0.4)

16 (0.5)

66 (0.4)

0.69

Primary diagnosis, n (%)

 Respiratory

5,940 (30.3)

1,099 (31.4)

4,841 (30.0)

0.12

 Gastrointestinal

3,342 (17.0)

520 (14.8)

2,822 (17.5)

<0.001

 Cardiovascular

2,822 (14.4)

448 (12.8)

2,374 (14.7)

0.003

 Sepsis

1,548 (7.9)

295 (8.4)

1,253 (7.8)

0.20

 Trauma

1,699 (8.7)

312 (8.9)

1,387 (8.6)

0.57

 Metabolic

1,640 (8.4)

315 (9.0)

1,325 (8.2)

0.14

 Neurologic

1,385 (7.1)

293 (8.4)

1,092 (6.8)

0.001

 Renal

626 (3.2)

121 (3.5)

505 (3.1)

0.33

 Other

620 (3.2)

102 (2.9)

518 (3.2)

0.35

Mechanical ventilation, n (%)

14,349 (73.1)

2,641 (75.3)

11,708 (72.6)

0.001

Source of admission, n (%)

 Emergency department

6,370 (32.5)

1,275 (36.4)

5,095 (31.6)

<0.001

 Operating room - Elective

3,165 (16.1)

401 (11.4)

2,764 (17.1)

<0.001

 Operating room – Emergency

3,438 (17.5)

508 (14.5)

2,930 (18.2)

<0.001

 Other hospital

3,140 (16.0)

603 (17.2)

2,537 (15.7)

0.032

 Ward

3,509 (17.9)

718 (20.5)

2,791 (17.3)

<0.001

Year of admission, n (%)

 2002/2003

3852 (19.6)

577 (14.9)

3275 (75.1)

<0.01*

 2004/2005

4929 (25.1)

801 (16.2)

4128 (83.8)

 

 2006/2007

5400 (27.5)

1007 (18.6)

4393 (81.4)

 

 2008/2009

5441 (27.7)

1120 (20.6)

4321 (79.4)

 

ICU LOS, (d) (med [IQR])

3 (1–7)

3 (1–7)

3 (2–7)

0.09

Source of discharge, n (%)

 Ward

17,935 (91.4)

3,199 (91.3)

14,736 (91.4)

0.75

 Acute care

979 (5.0)

260 (7.4)

719 (4.5)

<0.001

 Home

585 (3.0)

31 (0.9)

554 (3.4)

<0.001

 Left without authorization

75 (0.4)

11 (0.3)

64 (0.4)

0.46

 Chronic care

48 (0.2)

4 (0.1)

44 (0.3)

0.08

Weekend discharges

4,676 (23.8)

779 (16.7)

3,897 (83.3)

0.014

Weekday discharges

14,946 (76.2)

2,726 (18.2)

12,220 (81.8)

0.014

  1. Legend: AIDS: Acquired Immune Deficiency Syndrome; ICU: Intensive Care Unit; LOS: Length of stay
  2. *Linear regression