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Table 6 Multivariate regression analyses of death odds for HIV inpatients by age, sex, LOS, and comorbidities

From: HIV disease burden, cost, and length of stay in Portuguese hospitals from 2000 to 2010: a cross-sectional study

Independent variables N (% dead) OR unadjusted 95% C.I. OR adjusted 95% C.I.
Age groups - years of age      
1 - 0 to 17 1,057 (2.9) 1   1  
2 - 18 to 45 40,635 (13.3) 5.068 (3.541–7.253) 4.318 (2.980–6.257)
3 - 46 to 65 12,803 (17.1) 6.837 (4.769–9.802) 5.556 (3.826–8.069)
4 - 66 and older 2,544 (22.9) 9.840 (6.803–4.232) 7.955 (5.424–11.669)
Sex      
Female 15,210 (11) 1   1  
Male 41,834 (15.6) 1.500 (1.417–1.589) 1.407 (1.326–1.494)
LOS median (alive/deceased) 11.0 / 12.0 1.005 (1.005–1.006) 1.004 (1.003–1.005)
Elixhauser comorbidity measures      
No comorbidity* 16,850 (9.7) 1   1  
Metastatic cancer 537 (41.5) 4.319 (3.632–5.136) 3.286 (2.732–3.952)
Weight loss 3,753 (30.8) 2.917 (2.710–3.140) 2.501 (2.312–2.704)
Fluid and electrolyte disorders 5,189 (29.9) 2.897 (2.715–3.091) 2.332 (2.176–2.499)
Lymphoma 1,471 (27.5) 2.319 (2.063–2.607) 2.260 (2.000–2.553)
Pulmonary circulation disorders 414 (22.9) 1.782 (1.416–2.244) 2.132 (1.651–2.754)
Cardiac arrhythmias 877 (31.1) 2.749 (2.379–3.178) 2.030 (1.734–2.375)
Solid tumor without metastasis 2,905 (24.1) 1.973 (1.806–2.156) 1.706 (1.552–1.876)
Coagulopathy 3,187 (23.8) 1.953 (1.794–2.126) 1.668 (1.524–1.825)
Blood loss and anemia 1,943 (22.6) 1.780 (1.596–1.985) 1.573 (1.403–1.764)
Peripheral vascular disorders 230 (23.9) 1.877 (1.385–2.544) 1.416 (1.025–1.956)
Congestive heart failure 1,029 (22.6) 1.765 (1.522–2.046) 1.403 (1.195–1.648)
Other neurological disorders 3,329 (20.2) 1.551 (1.420–1.694) 1.364 (1.242–1.498)
Paralysis 708 (21.6) 1.654 (1.380–1.981) 1.331 (1.097–1.614)
Renal failure 1,929 (18.9) 1.403 (1.248–1.576) 1.221 (1.080–1.381)
Peptic ulcer disease excluding bleeding 205 (20.5) 1.537 (1.094–2.159) 1.208 (0.843–1.733)
Alcohol abuse 4,578 (18.1) 1.348 (1.245–1.459) 1.151 (1.057–1.253)
Liver disease 13,905 (15.2) 1.087 (1.030–1.147) 1.027 (0.969–1.088)
Hypertension, uncomplicated 2,191 (12.7) 0.861 (0.757–0.978) 0.685 (0.597–0.785)
Chronic pulmonary disease 2,458 (11) 0.726 (0.638–0.825) 0.542 (0.470–0.625)
Depression 1,597 (9.8) 0.642 (0.544–0.759) 0.533 (0.447–0.635)
Nutrient-deficiency anemia 1,889 (10.7) 0.706 (0.609–0.818) 0.531 (0.455–0.621)
Obesity 225 (7.1) 0.455 (0.273–0.757) 0.474 (0.281–0.799)
  1. *Patients with each comorbidity were compared with patients without that comorbidity. Some Elixhauser comorbidities had no influence on the nonadjusted model and were not included in the analysis, namely rheumatoid arthritis/collagen vascular diseases, psychoses, drug abuse, valvular heart disease, diabetes (both uncomplicated and complicated), complicated hypertension, and hypothyroidism.
  2. LOS = length of hospital stay; OR = odds ratio; 95% CI = 95% confidence interval.