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Table 3 Standardized total, direct, and indirect effects

From: Determining the predictors of innovation implementation in healthcare: a quantitative analysis of implementation effectiveness

 

Total effect

Direct effect

Indirect effect

Outcome: Enrollment in NCI-Sponsored Cancer Clinical Trials in 2011

Perceptions of Implementation Climate

0.285*

0.285*

N/A

Organizational Implementation Policies and Practices (IPP)

0.069*

N/A

0.069*

  Age

−0.264*

−0.179

−0.085

  Hospital-Based^

−0.043

−0.066

0.023

  Solo Practice^

−0.001

0.034

−0.035

  Non U.S. Trained

−0.035

−0.011

−0.024

  PI

0.356*

0.322*

0.034

  Tenure

0.224

0.117

0.107

  Oncology+

−0.097

−0.075

−0.022

  Radiation Oncology+

−0.162*

−0.120

−0.042

  Surgery+

−0.114

−0.077

−0.037

  Other Specialty+

−0.147*

−0.120

−0.027

  Organizational Size

0.028*

N/A

0.028*

  Structure: Hospital Cancer Center++

0.047*

N/A

0.047*

  Structure: Research Institute++

0.016*

N/A

0.016*

  Structure: Other++

0.024*

N/A

0.024*

  Organizational Maturity

0.000

N/A

0.000

  1. Model Fit Statistics: CFI = 0.933; TLI = 0.918; RMSEA = 0.045; SRMR = 0.048.
  2. Note: Total effects is the sum of direct and indirect effects.
  3. Note: Indirect effects are the product of the regression coefficients leading to the outcome. For example for OIPP, OIPP predicts perceptions and perceptions predicts enrollment. The indirect effect and subsequently the total effect of OIPP on enrollment equals the product of the two regression coefficients (From Figure 3) 0.243*0.285 = 0.069.
  4. *Statistically Significant (p < 0.05).
  5. ^Compared to Group Practice.
  6. +Compared to General Non-Specialized Oncology.
  7. ++Compared to Separate Non-Profit Structure.