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Table 1 Characteristics of the five newly marketed drugs included in the study

From: Is new drug prescribing in primary care specialist induced?

New drug (Brand name) Market introduction Main indication Reference group
Salmeterol/fluticasone (Seretide/Advair) 1999, May Asthma/COPD* Long acting β2-agonist and ICS
Rofecoxib (Vioxx) 2000, Apr Rheumatoid arthritis NSAIDs excl. low-dose aspirin
Esomeprazole (Nexium) 2000, Nov Gastro-oesophageal reflux Proton pomp inhibitors
Tiotropium (Spiriva) 2002, Jun COPD Ipratropiumbromide containing products
Rosuvastatin (Crestor) 2003, Mar Hypercholesterolemia HMG CoA reductase inhibitors
  1. *COPD: Chronic Obstructive Pulmonary Disease