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Table 2 Adjusted predictors of discontinuation of first antidiabetic drug therapy during a 24-month follow-up period

From: Racial differences in long-term adherence to oral antidiabetic drug therapy: a longitudinal cohort study

  Sulfonylurea (N = 1640) Metformin (N = 266)
Variable Hazard Ratio 95% Confidence Interval Hazard Ratio 95% Confidence Interval
Black vs. White 1.8 1.2, 2.7†† 1.5 0.4, 5.0
Male vs. Female 1.14 0.8, 1.6 1.6 0.6, 4.9
Age 1.02 1.01, 1.04 1.0 0.9, 1.0
Low Income 1.0 0.7, 1.5 3.3 0.9, 11.5
< High School Education 0.5 0.1, 1.9 1.0 0.07, 14.1
HbA1c 7.0–9.0 vs. <7.0§ 0.8 0.6, 1.3 0.4 0.05. 3.1
HbA1c > 9.0 vs. <7.0§ 1.01 0.5, 1.9 4.6 0.5, 42.2
BMI (time-variant) 1.001 1.0, 1.03 1.0 0.9, 1.1
# AHFS|| (time-variant) 0.9 0.8, 1.1 0.9 0.5, 1.7
# of MD Visits (time-variant) 1.0 0.8, 1.2 1.2 0.5, 2.5
  1. Analysis adjusted for health centers with disproportionately high numbers of black patients
  2. p < .05; ††p < .01.
  3. §Glycemic control based on baseline HbA1c levels.
  4. || AHFS = American Hospital Formulary Services Dispensed.