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Table 2 Adjusted predictors of discontinuation of first antidiabetic drug therapy during a 24-month follow-up period

From: Racial differences in long-term adherence to oral antidiabetic drug therapy: a longitudinal cohort study

 

Sulfonylurea (N = 1640)

Metformin (N = 266)

Variable

Hazard Ratio

95% Confidence Interval

Hazard Ratio

95% Confidence Interval

Black vs. White

1.8

1.2, 2.7††

1.5

0.4, 5.0

Male vs. Female

1.14

0.8, 1.6

1.6

0.6, 4.9

Age

1.02

1.01, 1.04

1.0

0.9, 1.0

Low Income

1.0

0.7, 1.5

3.3

0.9, 11.5

< High School Education

0.5

0.1, 1.9

1.0

0.07, 14.1

HbA1c 7.0–9.0 vs. <7.0§

0.8

0.6, 1.3

0.4

0.05. 3.1

HbA1c > 9.0 vs. <7.0§

1.01

0.5, 1.9

4.6

0.5, 42.2

BMI (time-variant)

1.001

1.0, 1.03

1.0

0.9, 1.1

# AHFS|| (time-variant)

0.9

0.8, 1.1

0.9

0.5, 1.7

# of MD Visits (time-variant)

1.0

0.8, 1.2

1.2

0.5, 2.5

  1. Analysis adjusted for health centers with disproportionately high numbers of black patients
  2. p < .05; ††p < .01.
  3. §Glycemic control based on baseline HbA1c levels.
  4. || AHFS = American Hospital Formulary Services Dispensed.