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Table 2 Nonadherence in antihypertensive use: results of the binomial multilevel analyses on early dropouts and continuers and on refill nonadherence

From: Patient risk profiles and practice variation in nonadherence to antidepressants, antihypertensives and oral hypoglycemics

  Early dropout (0 = continuer; 1 = early dropout) Refill adherence (0 = adherent > 80%; 1 = nonadherent)
  Odds ratioa) 95% CI Odds ratioa) 95% CI
Socio-demographic characteristics     
- age (mean; SD) 0.95* [0.95–0.96] 1.00 [0.99–1.00]
- % woman 1.29* [1.09–1.54] 1.08 [0.95–1.23]
- % college/university 1.34* [1.06–1.69] 1.04 [0.85–1.27]
- % non-western 2.22* [1.53–3.24] 1.44 [0.97–2.15]
- % private insurance 1.12 [0.93–1.35] 1.09 [0.95–1.25]
- % living together 0.94 [0.71–5.17] 0.88 [0.77–1.02]
- % with job/study 1.08 [0.88–1.32] 1.07 [0.89–1.27]
Medication     
Antihypertensives     
- % users of beta blockers 0.59* [0.49–0.72] 0.50* [0.44–0.57]
- % users of diuretics ref.   reference  
- % users of ace-inhibitors/A2 antagonists 0.25* [0.17–0.36] 0.37* [0.31–0.45]
- % users of other antihypertensives 0.58* [0.43–0.78] 0.30* [0.23–0.38]
Complex regime     
number of other ATCs (mean;sd) 0.94* [0.92–0.96] 0.97* [0.96–0.99]
Health & morbidity in general practice     
Self-reported health     
% excellent/good 1.51* [1.27–1.81] 0.93 [0.82–1.05]
Diagnoses for which GP is consulted (% of patients)     
Diabetes (T90) 0.46* [0.33–0.65] 0.69* [0.60–0.91]
Hypertension (K85–K87) 0.11* [0.08–0.13] 0.77* [0.64–0.78]
Other diagnoses in K-chapter (from K70–K99) 0.76* [0.62–0.78] 1.08 [0.98–1.24]
Hypercholesterolemia (T93) 0.50* [0.32–0.78] 0.88 [0.94–1.10]
GP consultation for chronic diseases and overall contact     
Number of other chronic complaints (mean, SD) 1.11* [1.02–1.21] 1.04 [0.98–1.11]
Number of contacts with GP (mean; SD) 1.04* [1.03–1.05] 1.02* [1.01–1.03]
Total (%)     
Number of patients (N) 14,219   12,110  
  1. * P < 0.05
  2. a) odds ratio > 1: more likely to be an early dropout; odds ratio < 1: less likely to be an early dropout