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Table 7 Reporting in guidelines of trials of antihypertensive medication a

From: Methods underpinning national clinical guidelines for hypertension: describing the evidence shortfall

Triala Yearb CMA 1999 WHO 1999 VHA 1999 SIGN 2001 ESH 2003 ICSI 2003 JNC 2003 SA 2003 BHS 2004 NICE 2004
VA-II[48] 1970 SR[49, 50] SR[49,51]   SR[49,51,52] SR[51]   SR[53] SR[51] SR[49]
HSCSG[54] 1974 SR[50] SR[51]   SR[51] SR[51]   SR[53] SR[51]  
USPHS[55] 1977 SR[50] SR[51]   SR[51] SR[51]   SR[53] SR[51]  
VA-NHLBI[56] 1978 SR[50] SR[51]   SR[51] SR[51]   SR[53] SR[51]  
HDFP[57-59] 1979 SR[49] SR[49,51]   SR[49,51,52,60] SR[51,61] SR[51] SR[49]
ANBPS[62] 1980   SR[51]   SR[51,52,60] SR[51,63]   SR SR[51]  
EWPHE[64,65] 1985 SR[49,50] SR[49,51,66]   SR[51,61]   SR[53] SR[51] SR[49]
IPPPSH[67] 1985          
MRC[68] 1985 SR[50]   SR[51]   SR[53] SR[51]  
Coope[69] 1986 SR[49] SR[49,51,66]   SR[51,61]   SR[53] SR[51] SR[49]
OSLO[70] 1986 SR[50] SR[51]   SR[51] SR[51]   SR[53] SR[51]  
SHEP-P[71-73] 1986 SR[50]    SR[60] SR[61]   SR[53]   
HAPPHY[74] 1987 SR[50]        
MAPHY[75] 1988          
CAPPP[76,77] 1990       
SHEP[78-81] 1991      
STOP-H[82] 1991 SR[49]   SR[61] SR[53]   SR[49]
SYST-EUR[83-86] 1991   SR[87]   
MRC-O[88] 1992 SR[50]   SR[61] SR[53]   SR[49]
STOP-H2[89-91] 1993 SR[92]    SR[63,87,93]   
NICS-EH[94,95] 1994 SR[92]     SR[63,87,93]     SR[63,96]
HOT[97] 1995  
PATS[98] 1995          
ALLHAT[99,100] 1996       
MIDAS[101,102] 1996 SR[50,92]        SR[63]
VHAS[103] 1997 SR[50,92]    SR[3,87,93]     SR[63,96]
ABCD[104] 1998 SR[92]     SR[87]  
FACET[105] 1998 SR[92]         
UKPDS[106] 1998    
HOPE[107] 2000    
INSIGHT[108,109] 2000 SR[92]        
NORDIL[110] 2000 SR[92]        
IDNT[111] 2001      SR[93]     SR[96]
PROGRESS[112] 2001      
RENAAL[113] 2001         
ELSA[114] 2002     SR[93]     SR[96]   
LIFE[115] 2002         
ANBP2[116,117] 2003      SR[93]     SR[96]
CONVINCE[118,119] 2003          SR[96]
SCOPE[120] 2003          SR[96]
JMIC-B[121] 2004      SR[96]      
VALUE[122-124] 2004          
  1. a Trials post-dating the guidelines (indicated by the stepped line) were not available to the guideline developers.
  2. b Year of earliest publication.
  3. c Referred only to rationale and design.
  4. Primary report of trial cited by guideline.
  5. SR Trial included in systematic review cited by guideline; primary report not cited by guideline.