Skip to main content

Table 1 Mean total number of drug prescriptions per GP per year, standardised per 1000 enlisted patients for the total intervention region versus a matched control group

From: Does a joint development and dissemination of multidisciplinary guidelines improve prescribing behaviour: a pre/post study with concurrent control group and a randomised trial

 

Desired direction of drug

pre

Short term

Δ short term

Long term

Δ Long term

  

I (n = 53)

C (n = 54)

I (n = 53)

C (n = 54)

I (n = 53)

C (n = 54)

I (n = 53)

C (n = 54)

I (n = 53)

C (n = 54)

Drug indicators

           

Antibiotics2

↓

639 (551,833)

491 (388,595)

667 (532,812)

489 (386,601)

3 (-56,70)

1 (-30,40)

652 (512,767)

486 (405,602)

-20 (-91,65)

-6 (-40,43)

Chinolones2

↓↓

37 (22,53)

24 (13,34)

36 (23,48)

22 (12,33)

1 (-12,9)

1 (-6,5)

34(27,44)

21 (14,31)

-4 (-10,4)

-1 (-7,5)

Nitrofurantoin1

↑

26 (19,33)

33 (27,39)

27 (22,33)

33 (26,40)

1 (-4,6)

0 (-3,3)

31(25,37)

37 (30,43)

5 (-1,10)

4 (0,8)

Trimethoprim1

↑

27 (20,33)

24 (18,30)

29 (21,36)

24 (18,29)

2 (-2,6)

-1 (-3,2)

26(20,32)

22 (17,28)

-1 (-6,5)

-2 (-6,2)

Amoxicillin with clav.acid2

↓

31 (24,51)

27 (18,41)

31 (19,46)

26 (17,41)

-3 (-10,8)

-1 (-8,5)

28(18,45)

28 (19,37)

-2 (-16,11)

0 (-10,5)

Amoxicillin2

↓

76 (48,126)

62 (37,94)

69 (34,112)

67 (44,100)

-6 (-53,20)

-1 (-12,8)

54(38,104)

58 (37,109)

-14 (-35,2)

-2 (-17,13)

Doxycyclin1

↓

133 (109,156)

83 (71,95)

126 (104,148)

79 (68,90)

-7 (-20,6)

-4 (-10,2)

114(93,135)

73 (62,84)

-19 (-35, -3)

-10 (-16, -4)

Mupirocin2

↓

5 (2,20)

5 (1,10)

5 (2,13)

5 (1,16)

-1 (-6,1)

1 (-2,5)*

5(2,11)

3 (1,12)

0 (-6,2)

0 (-3,2)

Cholesterol synthesis inhibitors (Statins) 1

↑↑

182 (154,209)

140 (115,164)

219 (188,249)

162 (136,189)

37 (28,46)

22 (16,29)

294 (248,339)

194 (164,224)

112 (87,137)

54 (41,66)*

Asthma & COPD

           

Long-term beta2-sympaticomimetics1

↑

40 (33,46)

40 (32,47)

37 (31,43)

37 (30,44)

-3 (-6, -1)

-3 (-6,0)

36(29,42)

31 (25,38)

-4 (-8,0)

-8 (-13, -4)

Asthma

           

Short-term beta2-sympaticomimetics2

↓

28 (21,44)

29 (19,35)

29 (18,39)

28 (19,41)

0 (-6,6)

2 (-3,7)

28(19,36)

27 (20,38)

-4 (-8,1)

-1 (-8,5)

Inhaled corticosteroids2

↑

21 (14,33)

19 (13,28)

19 (10,28)

21 (13,33)

-3 (-8,0)

-1 (-5,4)

14(9,23)

18 (11,26)

-7 (-11, -2)

-2 (-10,1)

COPD

           

Short-term beta2-sympaticomimetics1

-

62 (54,70)

42 (34,49)

61 (52,70)

42 (34,49)

-2 (-6,3)

0 (-3,4)

59(50,69)

36(29,42)

-3(-8,2)

-6 (-10, -2)

Inhaled corticosteroids1

↓

55 (46,64)

51 (42,59)

51 (42,60)

48 (39,57)

-5 (-8, -1)

-3 (-6,1)

41(33,48)

40(32,48)

-15(-20, -10)

-10 (-15, -6)

  1. 1. Mean (CI) for normally distributed variables
  2. 2. Median (P25-P75 intervals) for skewed variables
  3. * T-test unpaired/Mann-Whitney p < 0.01