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Table 2 MS charges a in 2011

From: Updated cost-of-care estimates for commercially insured patients with multiple sclerosis: retrospective observational analysis of medical and pharmacy claims data

  N % of Total Mean [SD] charge per patient ($) PValue
All patients 15,902 100.0 26,520 [38,478]  
By patient characteristics     
Gender     <0.001b
 Female 12,100 76.1 26,224 [38,716]  
 Male 3,801 23.9 27,445 [37,691]  
 Unknown 1 0.0 90,704 [NA]  
Age in years     <0.001
 17 or younger 126 0.8 14,142 [40,310]  
 18 to 25 405 2.6 25,731 [44,296]  
 26 to 35 2,009 12.6 26,324 [36,224]  
 36 to 45 4,021 25.3 27,430 [36,866]  
 46 to 55 5,030 31.6 27,558 [39,653]  
 56 to 64 3,499 22.0 25,876 [38,022]  
 65 or older 812 5.1 21,167 [42,005]  
Region     
 Northeast 1,861 11.7 27,035 [38,558] 0.646
 Midwest 4,480 28.2 25,820 [32,754]  
 South 6,730 42.3 26,604 [40,196]  
 West 2,827 17.8 27,093 [42,457]  
 Other 4 0.0 23,745 [28,601]  
Insurance product     0.032
 EPO 2,088 13.1 27,933 [42,360]  
 HMO 1,474 9.3 24,628 [33,046]  
 Indemnity 329 2.1 22,127 [39,181]  
 POS 11,336 71.3 26,648 [38,173]  
 PPO 641 4.0 26,622 [41,918]  
 Other 34 0.2 19,353 [28,310]  
Charge components Utilization c Mean [SD] Mean [SD] Cost ($) % of Total Cost
 Inpatientd 0.48 [2.75] 3,179 [17,860] 12.0
 Outpatientd 6.05 [8.04] 9,355 [24,523] 35.3
 Emergency Roomd 0.03 [0.39] 33 [522] 0.1
 DMD 3.17 [4.87] 13,953 [21,704] 52.6
  1. aSum of the charges for (1) medical claims with an MS diagnosis (ICD-9-CM = 340.xx in any diagnosis field or a DRG code for MS and cerebellar ataxia [DRG = 058, 059, or 060]) plus (2) medical or pharmacy claims indicating a DMD (Table 1).
  2. bExcluding the patient with unknown gender (i.e., t-test for female versus male).
  3. cNumber of claims. Claims counts for DMDs include both medical and pharmacy claims.
  4. dCharges for medical claims with an MS diagnosis (ICD-9-CM = 340.xx in any diagnosis field or a DRG code for MS and cerebellar ataxia [DRG = 058, 059, or 060]).
  5. DMD = disease-modifying drug; DRG = Diagnosis-Related Group; EPO = exclusive provider organization; HMO = health maintenance organization; MS = multiple sclerosis; NA = not applicable; POS = point of service; PPO = preferred provider organization; SD = standard deviation.
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