From: Drug costs in the management of metastatic castration-resistant prostate cancer in Canada
Medication | Dosage (reference) | Unit cost (reference) | Cost per month | ||
---|---|---|---|---|---|
Primary medication | |||||
Bicalutamide (Casodex) | 1 × 50 mg daily | [17] | $1.61 per tablet (50 mg) | [42] | $58.71 |
Abiraterone (Zytiga) | 4 × 250 mg daily | [34] | $28.3333 per tablet (250 mg) | [42] | $3,448 |
Cabazitaxel (Jevtana) | 25Â mg/m2 i.v. every 21Â days | [36] | $5,840 per vial (60Â mg/1.5Â ml) | [46] | $8,460* |
Docetaxel (Taxotere) | 75Â mg/m2 i.v. every 21Â days | [26] | $599.79 per vial (160Â mg/16Â ml)** | [46] | $774* |
Prednisone (Deltasone) | 2 × 5 mg daily | [34] | $0.022 per tablet (5 mg)** | [42] | $1.34 |
Premedication for chemotherapy-induced side effects | |||||
Dexamethasone†‡ | 8 mg i.v. every 21 days | $3.24 per vial (10 mg/ml, 1 ml)** | [46] | $4.69 | |
Diphenhydramine†| 25 mg i.v. every 21 days | [36] | $2.98 per vial (50 mg/ml, 1 ml)** | [46] | $4.32 |
Famotidine†| 20 mg i.v. every 21 days | [36] | $2.71 per vial (10 mg/ml, 2 ml)** | [46] | $3.93 |
Medication for medical castration | |||||
Goserelin (Zoladex) | 10.8 mg s.c. every 3 months (13 weeks) | [40] | $1,113 per 10.8 mg depot 3 months | [42] | $371 |
Bone-targeted therapy | |||||
Denosumab (XGEVA) | 120 mg s.c. every 4 weeks | [23] | $538.45 per vial (120 mg/1.7 ml) | [42] | $585 |