The cost-utility of open prostatectomy compared with active surveillance in early localised prostate cancer

Koerber, Florian; Waidelich, Raphaela; Stollenwerk, Björn; Rogowski, Wolf

doi:10.1186/1472-6963-14-163

BMC Health Services Research

Table 10 Transition probabilities

From: The cost-utility of open prostatectomy compared with active surveillance in early localised prostate cancer

State	Event	Expected value	SE	Source*
AS	Progression of Gleason Score	0.0263	0.007
	Other Progression (DRE/PSA)	0.0268	0.007
	Choosing treatment	0.018	0.005
	Developing metastatic prostate cancer under active surveillance	0.0023	0.000425	Bill-Axelson [7]; own calculation
	Infection due to biopsy	0.02	0.0075	Cambell-Walsh Urology
	Develop benign prostate hyperplasia	Age dependent		Andersson 2004 [48]
	Transurethral resection of the prostate due to benign prostate hyperplasia	0.000462	-	Andersson 2004; own calculation
Treatment	Perioperative death	0.0044	0.00001
	Major complication during surgery	0.0472	0.0168
	Urethral stricture	0.0344	0.002
Post PE	Incontinence and erectile dysfunction short term	0.37	0.0467
	Erectile dysfunction short term	0.39	0.0384
	Incontinence short term	0.09	0.0113
	Keep incontinence and erectile dysfunction long term	0.27	0.0338
	Keep incontinence long term	0.28	0.035
	Keep erectile dysfunction long term	0.89	0.0831
	Disease recurrence	0.00875	0.0032
	Progression from recurrence to metastatic disease	0.0127	0.0047	Horwitz 2005 [49]
	Death due to prostate cancer after development of metastatic state during hormonal therapy	0.022	0.0225	Alibhai [44]
Post RT	Incontinence short term	0.3	0.0835
	Bowel problems short term	0.18	0.0506
	Bowel problems and incontinence short term	0.054	0.0068
	Keep incontinence long term	0.16	0.02
	Keep bowel problems long term	0.152	0.019
	Erectile dysfunction long term	0.064	0.016
	Keep incontinence and bowel problems long term	0.148	0.0148
IC	Sphincter/sling surgery	0.05	0.0075
ED	Prosthesis surgery	0.02	0.0003
Death	Death due to other reasons	Age dependent	-

*If not stated otherwise: [45].
AS = Active Surveillance, ED = Erectile Dysfunction.
DRE = Digital Rectal Examination, IC = Incontinence.
PSA = Prostate Specific Antigen.
PE = Prostatectomy.
RT = Radiotherapy.

Back to article page

ISSN: 1472-6963

Contact us

General enquiries: journalsubmissions@springernature.com