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Table 3 Specialist recommendations and follow-up outcomes

From: Implementing antiretroviral resistance testing in a primary health care HIV treatment programme in rural KwaZulu-Natal, South Africa: early experiences, achievements and challenges

Specialist recommendation n Regimen prescribed matched regimen recommended by specialist Regimen prescribed did not match regimen recommended by specialist Continued first-line regimen despite recommendation for switch Data missing
Standard second-line ART* 324 247 (76.2) 17 (5.2) 39 (12.0) 21 (6.5)
Other standard second-line ART† 41 22 (53.7) 9 (22.0) 8 (19.5) 2 (4.9)
Non-standard second line ART‡ 21 7 (33.3) 10 (47.6) 1 (4.8) 3 (14.3)
Non-standard salvage regimen§ 3 0 2 (66.7) 1 (33.3) 0
Continue first-line ART 49 39 (79.6) 10 (20.4) NA 0
Total 438 (100) 315 (71.9) 48 (11.0) 49 (11.2) 26 (5.9)
  1. *Second-line regimen recommended by national guidelines in the absence of genotypic resistance testing (based on treatment history).
  2. Second-line regimen included in national guidelines but not the regimen that would have been prescribed based on treatment history.
  3. Alternative second-line regimen incorporating only drugs in national guidelines (e.g. 3 nucleoside reverse-transcriptase inhibitors and protease inhibitor).
  4. §Alternative regimen incorporating novel antiretroviral agents (e.g. raltegravir, etravirine).