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Table 2 Attitudes towards oxime therapy and AChE testing †

From: Effect of acetylcholinesterase (AChE) point-of-care testing in OP poisoning on knowledge, attitudes and practices of treating physicians in Sri Lanka

Question Response Level of AChE experience pvalue
"0 tests" n (%) "1-5 tests" (%) "5-20 tests" n (%)
What dose of intravenous pralidoxime would you prescribe to a severely symptomatic patient? None 0 (0%) 1 (14%) 0 (0%) 0.008
1 g 6 hourly 10 (91%) 6 (86%) 1 (25%)
2 g bolus + 500 mg continuous IV infusion 1 (9%) 0 (0%) 3 (75%)
For what duration would you give the above dose? None 0 (0%) 1 (14%) 0 (0%) 0.089
24 hours 1 (11%) 0 (0%) 0 (0%)
48 hours 6 (67%) 5 (71%) 0 (0%)
Other time period 2 (22%) 1 (14%) 3 (100%)
What dose of intravenous pralidoxime would you prescribe to a mildly symptomatic patient? None 1 (9%) 4 (57) 1 (25%) 0.105
1 g 6 hourly 10 (91%) 3 (43) 2 (50%)
2 g bolus + 500 mg continuous IV infusion 0 (0%) 0 (0%) 1 (25%)
For what duration would you give the above dose? None 1 (11%) 4 (57%) 1 (33%) 0.116
24 hours 0 (0%) 0 (0%) 1 (33%)
48 hours 7 (78%) 3 (43%) 1 (33%)
Other time period 1 (1%) 0 (0%) 0 (0%)
What dose of intravenous pralidoxime would you prescribe to an asymptomatic patient who is not getting atropine? None 6 (64%) 7 (100%) 4 (100%) 0.097
1 g 6 hourly 4 (36%) 0 (0%) 0 (0%)
2 g bolus + 500 mg continuous infusion 0 (0%) 0 (0%) 0 (0%)
For what duration would you give the above dose? None 5 (56%) 4 (100%) 4 (100%) 0.435
24 hours 2 (22%) 0 (0%) 0 (0%)
48 hours 2 (22%) 0 (0%) 0 (0%)
Other time period 0 (0%) 0 (0%) 0 (0%)
Do you think an acetylcholinesterase level (AChE) will be helpful in guiding treatment with oximes? Yes 8 (73%) 6 (86%) 1 (25%) 0.051
Not sure 3 (27%) 1 (14%) 1 (25%)
No 0 (0%) 0 (0%) 2 (50%)
Is this test was available and affordable. Would it be useful in treating OP poisoning? Yes 9 (100%) 6 (100%) 2 (50%) 0.035
No 0 (0%) 0 (0%) 2 (50%)
  1. † The total number of answers for each question do not always add up to 22 as some respondents omitted answering questions.