Table 2 Attitudes towards oxime therapy and AChE testing â€
Question | Response | Level of AChE experience | pvalue | ||
|---|---|---|---|---|---|
"0 tests" n (%) | "1-5 tests" (%) | "5-20 tests" n (%) | |||
What dose of intravenous pralidoxime would you prescribe to a severely symptomatic patient? | None | 0 (0%) | 1 (14%) | 0 (0%) | 0.008 |
1Â g 6 hourly | 10 (91%) | 6 (86%) | 1 (25%) | ||
2 g bolus + 500 mg continuous IV infusion | 1 (9%) | 0 (0%) | 3 (75%) | ||
For what duration would you give the above dose? | None | 0 (0%) | 1 (14%) | 0 (0%) | 0.089 |
24Â hours | 1 (11%) | 0 (0%) | 0 (0%) | ||
48Â hours | 6 (67%) | 5 (71%) | 0 (0%) | ||
Other time period | 2 (22%) | 1 (14%) | 3 (100%) | ||
What dose of intravenous pralidoxime would you prescribe to a mildly symptomatic patient? | None | 1 (9%) | 4 (57) | 1 (25%) | 0.105 |
1Â g 6 hourly | 10 (91%) | 3 (43) | 2 (50%) | ||
2 g bolus + 500 mg continuous IV infusion | 0 (0%) | 0 (0%) | 1 (25%) | ||
For what duration would you give the above dose? | None | 1 (11%) | 4 (57%) | 1 (33%) | 0.116 |
24Â hours | 0 (0%) | 0 (0%) | 1 (33%) | ||
48Â hours | 7 (78%) | 3 (43%) | 1 (33%) | ||
Other time period | 1 (1%) | 0 (0%) | 0 (0%) | ||
What dose of intravenous pralidoxime would you prescribe to an asymptomatic patient who is not getting atropine? | None | 6 (64%) | 7 (100%) | 4 (100%) | 0.097 |
1Â g 6 hourly | 4 (36%) | 0 (0%) | 0 (0%) | ||
2 g bolus + 500 mg continuous infusion | 0 (0%) | 0 (0%) | 0 (0%) | ||
For what duration would you give the above dose? | None | 5 (56%) | 4 (100%) | 4 (100%) | 0.435 |
24Â hours | 2 (22%) | 0 (0%) | 0 (0%) | ||
48Â hours | 2 (22%) | 0 (0%) | 0 (0%) | ||
Other time period | 0 (0%) | 0 (0%) | 0 (0%) | ||
Do you think an acetylcholinesterase level (AChE) will be helpful in guiding treatment with oximes? | Yes | 8 (73%) | 6 (86%) | 1 (25%) | 0.051 |
Not sure | 3 (27%) | 1 (14%) | 1 (25%) | ||
No | 0 (0%) | 0 (0%) | 2 (50%) | ||
Is this test was available and affordable. Would it be useful in treating OP poisoning? | Yes | 9 (100%) | 6 (100%) | 2 (50%) | 0.035 |
No | 0 (0%) | 0 (0%) | 2 (50%) | ||