|
Demographics
|
|
Age (years)
| |
estimate
|
CI
|
estimate
|
CI
|
HR
|
CI
|
| |
20-59
|
81.70%
|
(43.8% to 119.7%)
|
24.62%
|
(4.04% to 45.20%)
|
0.38
|
(0.27 to 0.53)
|
| |
60-64
|
85.60%
|
(44.8% to 126.3%)
|
31.74%
|
(9.90% to 53.58%)
|
0.37
|
(0.25 to 0.55)
|
| |
65-69
|
95.40%
|
(55.5% to 135.3%)
|
38.45%
|
(16.91% to 59.98%)
|
0.38
|
(0.26 to 0.54)
|
| |
70-74
|
75.80%
|
(41.9% to 109.7%)
|
30.56%
|
(11.53% to 49.60%)
|
0.48
|
(0.36 to 0.64)
|
| |
75-79
|
69.60%
|
(38.4% to 100.8%)
|
30.10%
|
(12.24% to 47.96%)
|
0.54
|
(0.42 to 0.71)
|
| |
80-84
|
24.90%
|
(0.4% to 49.4%)
|
19.94%
|
(2.96% to 26.93%)
|
0.81
|
(0.64 to 1.02)
|
| |
85 years and over (reference)
| | | | | | |
|
Gender
|
| |
male (reference)
| | | | | | |
| |
Female
|
−14.80%
|
(−24.0% to −5.6%)
|
−12.74%
|
(20.21% to −5.27%)
|
1.09
|
(0.92 to 1.30)
|
|
Race
|
| |
white (reference)
| | | | | | |
| |
non-white
|
−0.10%
|
(−22.1% to 21.9%)
|
3.48%
|
(−14.58% to 21.54%)
|
1.33
|
(0.90 to 1.97)
|
|
Clinical findings and measurements
|
|
BMI (kg/m2)
|
| |
<25
|
−11.00%
|
(−26.7% to 4.6%)
|
13.16%
|
(−2.11% to 28.43%)
|
1.78
|
(1.31 to 2.42)
|
| |
25-34
|
−0.40%
|
(−13.4% to 12.6%)
|
4.52%
|
(−6.61% to 15.66%)
|
1.24
|
(0.94 to 1.63)
|
| |
>=35 (reference)
| | | | | | |
|
Smoking Status
|
| |
current smoker
|
−24.80%
|
(−37.9% to −11.8%)
|
−21.58%
|
(−32.74% to −10.41%)
|
1.28
|
(0.96 to 1.70)
|
| |
never or former smoker (reference)
| | | | | | |
|
Systolic blood pressure (mm/hg)
|
| |
<120
|
−8.00%
|
(−20.3% to4.3%)
|
4.29%
|
(−6.38% to 14.97%)
|
1.41
|
(1.14 to 1.74)
|
| |
120-140
|
−10.10%
|
(−20.5% to 0.2%)
|
−2.40%
|
(−11.08% to 6.29%)
|
1.26
|
(1.03 to 1.55)
|
| |
>140 (reference)
| | | | | | |
|
Hemoglobin
|
| |
<11gm/dl
|
−20.10%
|
(−36.7% to −3.6%)
|
33.27%
|
(14.18% to 52.37%)
|
2.08
|
(1.70 to 2.53)
|
| |
>= 11gm/dl (reference)
| | | | | | |
|
Renal function* (ml/min/1.73m2)
|
| |
>=60
|
24.60%
|
(−10.1% to 59.4%)
|
−44.73%
|
(−54.85% to −34.61%)
|
0.35
|
(0.27 to 0.45)
|
| |
45-60
|
38.10%
|
(−1.6% to 77.8%)
|
−36.75%
|
(−48.68% to −24.81%)
|
0.40
|
(0.30 to 0.52)
|
| |
30-45
|
24.70%
|
(−12.8% to 62.1%)
|
−31.49%
|
(−44.97% to −18.01%)
|
0.57
|
(0.44 to 0.74)
|
| |
<30 (reference)
| | | | | | |
|
Ejection fraction on echocardiogram(%)
|
| |
>65
|
52.70%
|
(1.5% to 103.4%)
|
−3.00%
|
(−26.81% to 20.81%)
|
0.43
|
(0.29 to 0.64)
|
| |
51-65
|
50.70%
|
(7.1% to 94.3%)
|
−15.37%
|
(−33.47% to 2.74%)
|
0.36
|
(0.27 to 0.49)
|
| |
41-50
|
44.70%
|
(0.3% to 89.0%)
|
−14.80%
|
(−34.20% to 4.60%)
|
0.39
|
(0.27 to 0.56)
|
| |
31-40
|
47.10%
|
(2.1% to 92.0%)
|
−16.09%
|
(−35.00% to 2.82%)
|
0.37
|
(0.26 to 0.53)
|
| |
21-30
|
50.50%
|
(4.3% to 96.8%)
|
−5.38%
|
(−26.83% to 16.07%)
|
0.44
|
(0.31 to 0.64)
|
| |
1-20 (reference)
| | | | | | |
|
Posterior wall thickness on echocardiogram (mm)
|
| |
<11
|
9.70%
|
(−2.0% to 21.4%)
|
9.83%
|
(69.90% to 18.96%)
|
1.10
|
(0.92 to 1.30)
|
| |
>=11 (reference)
| | | | | | |
|
Comorbid diagnoses
|
|
Atrial fibrillation
|
yes
|
15.30%
|
(3.1% to 27.6%)
|
26.75%
|
(16.72% to 36.79%)
|
1.08
|
(0.91 to 1.27)
|
| |
no (reference)
| | | | | | |
|
Aortic valvular disease
|
yes
|
0.40%
|
(−10.5% to 11.3%)
|
9.25%
|
(35.73% to 18.14%)
|
1.22
|
(1.03 to 1.44)
|
| |
no (reference)
| | | | | | |
|
Coronary artery disease
|
yes
|
13.90%
|
(1.9% to 26.0%)
|
19.86%
|
(10.19% to 29.53%)
|
1.09
|
(0.91 to 1.31)
|
| |
no (reference)
| | | | | | |
|
Chronic lung disease
|
yes
|
29.20%
|
(16.3% to 42.0%)
|
44.95%
|
(33.82% to 56.08%)
|
1.25
|
(1.06 to 1.47)
|
| |
no (reference)
| | | | | | |
|
Depression
|
yes
|
36.20%
|
(18.6% to 53.8%)
|
64.00%
|
(48.85% to 79.16%)
|
1.31
|
(1.08 to 1.58)
|
| |
no (reference)
| | | | | | |
|
Diabetes
|
yes
|
37.80%
|
(22.5% to 53.0%)
|
64.82%
|
(51.37% to 78.26%)
|
1.38
|
(1.16 to 1.65)
|
| |
no (reference)
| | | | | | |
|
Hypothyroidism
|
yes
|
1.40%
|
(−13.1% to 15.8%)
|
21.20%
|
(9.36% to 33.05%)
|
1.25
|
(1.02 to 1.52)
|
| |
no (reference)
| | | | | | |
|
Hyperlipidemia
|
yes
|
21.40%
|
(8.4% to 34.4%)
|
14.35%
|
(5.11% to 23.60%)
|
0.87
|
(0.73 to 1.04)
|
| |
no (reference)
| | | | | | |
|
Peripheral vascular disease
|
yes
|
13.20%
|
(−4.0% to 30.3%)
|
37.31%
|
(23.46% to 51.16%)
|
1.33
|
(1.10 to 1.62)
|
| |
no (reference)
| | | | | | |
|
Stroke
|
yes
|
−0.80%
|
(−19.0% to 17.4%)
|
19.08%
|
(4.99% to 33.16%)
|
1.37
|
(1.10 to 1.71)
|
| |
no (reference)
| | | | | | |
|
Transient ischemic attack
|
yes
|
18.00%
|
(−5.4% to 41.5%)
|
4.44%
|
(−11.27% to 20.16%)
|
0.84
|
(0.63 to 1.14)
|
| |
no (reference)
| | | | | | |
