Table 2 Treatment response (defined as 50% change from baseline sum score) in physicians’ assessment using HAMD-17 item scale and by patients’ self-assessment using B-PHQ 9 questionnaire, and HAMD-17 sum scores and B-PHQ 9 sum scores at 6 month and at 12 month in the intervention group and in the group treated as usual, all analyses adjusted for age
Intervention | Treatment as usual | p-value | |
|---|---|---|---|
Physicians’ assessment | |||
Response in HAMD-17 score at 6 months (n, %), n = 45 | 6 (50) | 14 (42) | 0.961 |
Missing values replaced by LOCF, n = 57 | 6 (38) | 15 (37) | 0.756 |
Response in HAMD-17 score at 12 months (n, %), n = 41 | 5 (83) | 19 (54) | 0.282 |
Missing values replaced by LOCF, n = 59 | 6 (38) | 20 (47) | 0.388 |
Depression severity by HAMD-17 score at 6 months (mean, SD), n = 45 | 10.5 (7.6) | 12.3 (7.8) | 0.718 |
Missing values replaced by LOCF, n = 58 | 12.8 (7.7) | 13.8 (8.3) | 0.954 |
Depression severity by HAMD-17 score at 12 months (mean, SD), n = 41 | 4.7 (8.0) | 11.2 (7.4) | 0.083 |
Missing values replaced by LOCF, n = 60 | 11.5 (8.1) | 12.8 (8.2) | 0.847 |
Patients’ self assessment | |||
Response in B-PHQ 9 score at 6 months (n, %), n = 44 | 10 (83) | 5 (16) | 0.000 |
Missing values replaced by LOCF, n = 60 | 10 (56) | 7 (17) | 0.002 |
Response in B-PHQ 9 score at 12 months (n, %), n = 38 | 4 (67) | 15 (47) | 0.346 |
Missing values replaced by LOCF, n = 60 | 7 (37) | 19 (43) | 0.887 |
Depression severity by B-PHQ 9 score at 6 months (mean, SD), n = 45 | 6.4 (5.2) | 11.5 (5.8) | 0.020 |
Missing values replaced by LOCF, n = 60 | 9.8 (6.9) | 11.7 (5.4) | 0.375 |
Depression severity by B-PHQ 9 score at 12 months (mean, SD), n = 42 | 7.9 (8.7) | 9.0 (5.2) | 0.858 |
Missing values replaced by LOCF, n = 60 | 10.6 (7.5) | 9.6 (5.1) | 0.428 |