| |
U.S. Data from Ernst et al. 2001 model [16]
|
German Data (Base Case)
|
|---|
|
Outcomes
|
Overall probability of therapeutic outcome*
|
Factor in relation to hospitalisation
|
Expected population developing an ADE and classification of resource utilization** (as % of population ingesting medications)
|
Unit cost (in 2007 €)
|
Total costs (million €)
|
|---|
|
No treatment
|
0.0207
|
1.912
|
260,873 (0.5)
| | |
|
Physician visit
|
0.0436
|
4.021
|
548,620 (1.1)
|
231
|
12.4
|
|
Additional treatment
|
0.0753
|
6.944
|
947,451 (1.9)
|
422+231 (653)
|
61.8
|
|
Emergency department
|
0.0166
|
1.531
|
208,887 (0.4)
|
4374
|
91.3
|
|
Hospital admissions
|
0.0108
|
1.000
|
136,447 (0.3)
|
34525
|
471.0
|
|
Long-term care
|
0.0028
|
0.254
|
34,615 (0.07)
|
48906
|
169.3
|
|
Death
|
0.0002
|
0.022
|
2,958 (0.006)
|
34527
|
10.2
|
|
Total costs
| | | | |
816.0
|
- *sum of probabilities associated with therapeutic outcomes in Figure 1 **calculated using the factor in relation to hospitalisation and the number of hospitalised persons; 1average cost of published physician visits [20] inflated to year 2007; 2average cost of a prescribed medication in 2007 [19]3Total cost of additional treatment comprises physician visit and prescription of a new medication 4average cost per hospital day [18]; 5average cost per hospital admission for an ADE in 2007 (calculated by authors); 6average cost of 6 months of long-term facility care in 2007 (total service expenditures [23] divided by total beneficiaries [24]; 7costs of death assume hospitalisation prior to death
