Assessment of surfactant use in preterm infants as a marker of neonatal intensive care unit quality

Table 1 Predictors of surfactant use in cohort 1 (n = 3,633)*

	Odds Ratio	95% CI	p-value
PATIENT-LEVEL PREDICTORS*
Gestational age
30 weeks (n = 621)	Reference
31 weeks (n = 620)	0.73	0.57-0.95	0.019
32 weeks (n = 747)	0.68	0.53-0.87	0.002
33 weeks (n = 715)	0.58	0.45-0.75	<0.001
34 weeks (n = 930)	0.69	0.55-0.88	0.003
Race†
Non-white (n = 840)	Reference
White (n = 2,571)	1.22	1.02-1.47	0.03
Gender
Female (n = 1,535)	Reference
Male (n = 2,098)	1.34	1.15-1.57	<0.001
Age at admission
Day of life 0 (n = 3,107)	Reference
Day of life 1 (n = 526)	1.11	0.89-1.38	0.34
Mode of respiratory support (first 48 hrs)
NCPAP (n = 672)	Reference
Mechanical ventilation (n = 2,961)	54.99	35.86-84.35	<0.001
HOSPITAL-LEVEL PREDICTORS††
Research involvement
Top 10 hospital based on NIH total awards to children's hospitals	1.48	0.98-2.25	0.065
Surgical volume
≥ 29% (median) of admissions to the NICU classified as surgical	1.58	0.79-3.16	0.193
Payer mix
≥ 45% (median) of admissions to the hospital paid by Medicaid	0.80	0.40-1.61	0.532
Patient volume
≥ 45 (median) Annual ELBW Admissions	1.80	1.02-3.19	0.042

NCPAP = nasal continuous positive airway pressure, NIH = National Institutes of Health; NICU = neonatal intensive care unit; ELBW = extremely low birth weight
*Model includes patient-level variables listed in the table plus hospital fixed effects
†Model includes a term for missing race (n = 222)
††Model includes patient-level variables listed in the table plus hospital characteristics added individually

ISSN: 1472-6963