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Table 2 Logistic regression results showing EDP impacts on medication adherence

From: Impact of prescription length supply policy on patient medication adherence in Thailand

Variables

Adjusted odds ratio

95% CI

P value

Intervention x Period

1.94

1.80–2.09

< 0.001

Age in group (years)

18–25

Reference

26–50

0.58

0.45–0.74

< 0.001

51–75

0.88

0.69–1.12

0.305

>75

0.97

0.76–1.24

0.803

Gender

Female

Reference

Male

1.12

1.09–1.14

< 0.001

Number of medications prescribed at the index date

>1

Reference

1

3.20

3.12–3.29

< 0.001

Has history of hospital admission

0.86

0.84–0.89

< 0.001

Class of medications

Sulfonylurea

0.19

0.18–0.19

< 0.001

Non-sulfonylurea

0.18

0.14–0.23

< 0.001

Metformin

0.50

0.49–0.52

< 0.001

Thiazolidinediones

0.21

0.19–0.22

< 0.001

Alpha-glucosidase inhibitors

0.36

0.34–0.39

< 0.001

DPP-4 inhibitors

0.42

0.39–0.44

< 0.001

SGLT-2 inhibitors

0.49

0.39–0.63

< 0.001

Statins

0.75

0.70–0.79

< 0.001

Comorbidities

   

Acute myocardial infarction

1.14

1.06–1.21

< 0.001

Congestive heart failure

0.82

0.78–0.87

< 0.001

Cerebrovascular disease

0.86

0.83–0.89

< 0.001

Dementia

1.22

1.14–1.32

< 0.001

Chronic pulmonary disease

0.87

0.82–0.92

< 0.001

Peptic ulcer disease

1.19

1.05–1.36

0.006

Mild liver disease

0.87

0.82–0.92

< 0.001

Diabetes without chronic complication

1.42

1.36–1.48

< 0.001

Diabetes with chronic complication

1.72

1.66–1.79

< 0.001

Hemiplegia

0.65

0.52–0.83

< 0.001

Cancer

0.70

0.63–0.78

< 0.001

Solid tumor

1.44

1.06–1.95

0.02

AIDs

1.36

1.13–1.63

< 0.001

CCI score

   

0

Reference

1

1.18

1.15–1.22

< 0.001

>2

1.23

1.18–1.29

< 0.001

  1. EDP, Extended Dispensing Policy; CCI, Charlson Comorbidity Index; AIDS, acquired immune deficiency syndrome