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Table 5 HF-related healthcare resource costs per patient during the index year

From: Healthcare resource utilization and costs among patients with heart failure with preserved, mildly reduced, and reduced ejection fraction in Spain

 

All HF patients (N = 21,297)

All HFrEF (N = 10,323)

All HFmrEF (N = 903)

All HFpEF (N = 8225)

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

P vs HFrEF

n

Total cost (€)

€1

€2

P vs HFrEF

Outpatient

21,297

5.060.168,4

237.6 (131.9)

238.1 (131.6)

10,323

3.524.686,7

341.4 (107.9)

341.4 (107.9)

903

137.349,4

152.1 (133)

152.8 (53.8)

 < 0.001

8225

1.124.159,4

136.7 (56.4)

137.3 (55.9)

 < 0.001

 GPs visitsa

21,297

4.555.605,93

213.9 (118)

215.6 (116.9)

10,323

3.046.516,68

295.1 (111.5)

295.2 (111.4)

903

134.919,42

149.4 (119.2)

150.7 (54.5)

 < 0.001

8225

1.103.774,43

134.2 (58.2)

136.6 (55.9)

 < 0.001

 Specialist visitsa

21,297

504.562,50

23.7 (41.3)

84.1 (31.1)

10,323

478.170,00

46.3 (48.5)

85.2 (31.8)

903

2.430,00

2.7 (41.8)

67.5 (0)

 < 0.001

8225

20.385,00

2.5 (12.7)

67.5 (0)

 < 0.001

Inpatient

 Hospitalizations (> 24 hs)b

21,297

39.504.394,50

1854.9 (4212.4)

6757.5 (5614)

10,323

27.597.079,10

2673.4 (5295)

8501.9 (6293.9)

903

1.296.756,90

1436.1 (4248.3)

5638.1 (4294.6)

 < 0.001

8225

8.945.087,50

1087.5 (2641.4)

4666.2 (3638.7)

 < 0.001

Pharmacy

 Prescriptionsc

21,297

5.187.669,82

243.6 (119.2)

243.6 (119.2)

10,323

2.612.507,32

253.1 (120.6)

253.1 (120.6)

903

191.566,65

212.1 (119.7)

212.1 (104.6)

 < 0.001

8225

1.929.884,67

234.6 (117.4)

234.6 (117.4)

 < 0.001

Indirect cost

 Cost of absence from workd

21,297

3.890.309,98

182.7 (669.1)

2366.4 (794.7)

10,323

3.482.130,05

337.3 (912.1)

2714.1 (492.4)

903

53.034,04

58.7 (680.9)

1233.3 (256.9)

 < 0.001

8225

271.242,80

33 (187.8)

1063.7 (201.8)

 < 0.001

Total HF-related cost

 

53.642.542,7

2518.8 (4323.8)

  

37.216.403,2

3605.2 (5379.6)

  

1.678.707,0

1859 (4361.4)

 

 < 0.001

 

12.270.374,4

1491.8 (2650.6)

 

 < 0.001

 

All HFpEF (50 to < 60%) (N = 2995)

All HFpEF (≥ 60%) (N = 5230)

All HFuEF (N = 1846)

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

Outpatient

2995

411.438,3

137.4 (55.8)

137.9 (55.3)

5230

712.721,2

136.3 (56.8)

136.9 (56.2)

1846

273.972,9

148.4 (51.6)

148.9 (51)

 GPs visitsa

2995

405.430,77

135.4 (57.5)

137.3 (55.5)

5230

698.343,66

133.5 (58.5)

136.1 (56.1)

1846

270.395,40

146.5 (52.8)

147.8 (51.1)

 Specialist visitsa

2995

6.007,50

2 (11.5)

67.5 (0)

5230

14.377,50

2.7 (13.3)

67.5 (0)

1846

3.577,50

1.9 (11.3)

67.5 (0)

Inpatient

 Hospitalizations (> 24 hs)b

2995

3.207.395,50

1070.9 (2608.9)

4615 (3603.2)

5230

5.737.692,00

1097.1 (2660.1)

4695.3 (3659.8)

1846

1.665.471,00

902.2 (2062.8)

3676.5 (2673.1)

Pharmacy

 Prescriptionsc

2995

699.218,57

233.5 (115.8)

233.5 (115.8)

5230

1.230.666,10

235.3 (118.3)

235.3 (118.3)

1846

453.711,18

245.8 (121.1)

245.8 (121.1)

Indirect cost

 Cost of absence from workd

2995

100.602,74

33.6 (191)

1081.7 (203.5)

5230

170.640,06

32.6 (185.9)

1053.3 (200.7)

1846

83.903,09

45.5 (245.6)

1331.8 (231.5)

Total HF-related cost

 

4.418.655,1

1475.3 (2622.6)

  

7.851.719,3

1501.3 (2666.8)

  

2.477.058,2

1341.9 (2083.1)

 
  1. aCost was calculated based on standard cost for GP/ specialist visits
  2. bCost of inpatient stays was calculated based on the DRG-based reimbursement of the stays
  3. cCost was based on full price of product
  4. dCost of absence from work was calculated by multiplying the number of days of absence from work due to sickness by the mean daily salary of a working person
  5. All cost were presented in euros
  6. €1 Mean cost per patient (SD), €2 Mean cost per patient (SD) accounting for patients with ≥ 1 resource use, GP General practitioner, HF Heart failure, HFmrEF Heart failure with mildly reduced ejection fraction, HFpEF Heart Failure with preserved ejection fraction, HFrEF Heart failure with reduced ejection fraction, HFuEF Heart Failure with unspecified ejection, HRCU Healthcare resource utilization, n number of patients, SD Standard deviation
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