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Table 3 Healthcare resource utilization during the index year

From: Healthcare resource utilization and costs among patients with heart failure with preserved, mildly reduced, and reduced ejection fraction in Spain

 

All HF patients (n = 21,297)

HFrEF (n = 10,323)

HFmrEF (n = 903)

P vs HFrEF

HFpEF (n = 8225)

P vs HFrEF

HFpEF (50 to < 60%) (n = 2995)

HFpEF (≥ 60%) (n = 5230)

HFuEF (n = 1846)

Length of hospital stays (all-cause)

 Number of patients hospitalized, n (%)

6652 (31.23)

3606 (34.93)

270 (29.90)

 < 0.001

2242 (27.26)

 < 0.001

814 (27.18)

1428 (27.30)

534 (28.93)

 Mean (SD)

19.59 (17.73)

24.93 (20.3)

16.18 (13.52)

13.51 (11.31)

13.43 (11.27)

13.56 (11.33)

10.73 (8.41)

 Median (25th, 75th percentile)

14 (7–25)

19 (10–35)

12 (7–19)

10 (5–18)

10 (5–18)

10 (5–19)

8 (5–15)

Length of hospital stays (HF-related)

 Number of patients hospitalized, n (%)

5846 (27.45)

3246 (31.44)

230 (25.47)

 < 0.001

1917 (23.31)

 < 0.001

695 (23.21)

1222 (23.37)

453 (24.54)

 Mean (SD)

21.06 (17.49)

26.49 (19.61)

17.57 (13.38)

14.54 (11.34)

14.38 (11.23)

14.63 (11.4)

11.46 (8.33)

 Median (25th, 75th percentile)

16 (9–27)

20 (13–36)

14 (9–21.5)

12 (6 -21)

12 (6–21)

12 (6–21)

9 (5–16)

Number of prescriptions (all-cause)

 Number of patients, n (%)

21,297 (100)

10,323 (100)

903 (100)

 < 0.001

8225 (100)

 < 0.001

2995 (100)

5230 (100)

1846 (100)

 Mean (SD)

38.86 (13.29)

41.39 (13.12)

34.3 (12.17)

36.23 (12.97)

36.24 (13)

36.22 (12.95)

38.67 (13.32)

 Median (25th, 75th percentile)

38 (29–47)

41 (32–50)

33 (26–42)

35 (27–45)

35 (27–44)

35 (27–45)

38 (29–48)

Number of prescriptions (HF-related)

 Number of patients, n (%)

21,297 (100)

10,323 (100)

903 (100)

 < 0.001

8225 (100)

 < 0.001

2995 (100)

5230 (100)

1846 (100)

 Mean (SD)

16.09 (7.77)

16.74 (7.85)

13.96 (6.84)

15.47 (7.64)

15.43 (7.57)

15.5 (7.68)

16.16 (7.89)

 Median (25th, 75th percentile)

15 (10–21)

16 (11–22)

13 (9–18)

15 (10–20)

15 (10–20)

15 (10–20)

15 (10–21)

Work absences (number of days) (all-cause)

 Number of patients, n (%)

3178 (14.92)

2011 (19.48)

93 (10.30)

 < 0.001

871 (10.59)

 < 0.001

321 (10.72)

550 (10.52)

203 (10.99)

 Mean (SD)

17.81 (9.89)

21.74 (10.2)

11.58 (3.41)

10.79 (3.68)

10.86 (3.56)

10.75 (3.75)

11.92 (4.25)

 Median (25th, 75th percentile)

15 (10–26)

23 (13–30)

12 (9–14)

11 (8–14)

11 (8–13)

11 (8–14)

13 (9–15)

Work absences (number of days) (HF-related)

 Number of patients, n (%)

1644 (7.72)

1283 (12.42)

43 (4.76)

 < 0.001

255 (3.10)

 < 0.001

93 (3.11)

162 (3.10)

63 (3.41)

 Mean (SD)

23.38 (7.85)

26.82 (4.86)

12.19 (2.54)

10.51 (1.99)

10.69 (2.01)

10.41 (1.98)

13.16 (2.29)

 Median (25th, 75th percentile)

24 (19–30)

27 (23–31)

13 (10–14)

11 (9–12)

11 (9–12)

10 (9–12)

13 (11–15)

Polypharmacy (not only HF treatments), n (%)

 1

20 (0.09)

5 (0.05)

0

 < 0.001

14 (0.17)

 < 0.001

4 (0.13)

10 (0.19)

1 (0.05)

 2

91 (0.43)

50 (0.48)

2 (0.22)

35 (0.43)

12 (0.4)

23 (0.44)

4 (0.22)

 3

369 (1.73)

128 (1.24)

19 (2.1)

193 (2.35)

71 (2.37)

122 (2.33)

29 (1.57)

 4

1512 (7.1)

486 (4.71)

99 (10.96)

786 (9.56)

310 (10.35)

476 (9.1)

141 (7.64)

 ≥ 5

19.305 (90.65)

9654 (93.52)

783 (86.71)

7197 (87.49)

2598 (86.75)

4599 (87.93)

1671 (90.52)

  1. HF Heart failure, HFmrEF Heart failure with mildly reduced ejection fraction, HFpEF Heart Failure with preserved ejection fraction, HFrEF Heart failure with reduced ejection fraction, HFuEF Heart Failure with unspecified ejection, HRCU Healthcare resource utilization, SD Standard deviation