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Table 3 Incremental cost-effectiveness ratio of alternate treatment strategy relative to standard autologous ART treatment

From: Which assisted reproductive technology (ART) treatment strategy is the most clinically and cost-effective for women of advanced maternal age: a Markov model

Age

PGT-A

Donor ART

Social Oocytes

Mean ICER (USD)

Mean ICER (USD)

Mean ICER (USD)

35

17,790 (−133,529 to 124,370)

26,240 (20,964 to 34,639)

36

7,997 (− 113,502 to 103,557)

19,674 (16,377 to 242,56)

37

3,282 (− 93,270 to 85,661)

15,850 (13,665 to 18,757)

38

250 (− 61,855 to 55,078)

23,244 (19,920 to 28,036)

39

More effective and cost saving

19,504 (17,056 to 22,758)

40

17,976 (4742 to 127,836)

17,732 (15,832 to 20,125)

More effective and cost saving

41

21,256 (−66,525 to 168,998)

13,422 (12,091 to 15,071)

More effective and cost saving

42

5,269 (1926 to 13,031)

12,189 (11,067 to 13,557)

More effective and cost saving

43

1,947 (101 to 5,107)

10,086 ( 9321 to10,990 )

More effective and cost saving

44

1,111 (− 366 to 3,513)

9,918 ( 9,225 to 10,758to )

More effective and cost saving

45

2,246 (537 to 5,683)

12,718 (11,899 to 13,900)

More effective and cost saving

  1. aSocial freezing strategy involves women cryopreserved her oocyte cryopreservation at age 32 and returning at age 40 or above for ART for thaw cycles
  2. 95% confidential interval in the parenthesis was derived from bootstrapped of 10,000 simulations USD: United States Dollars; ICER: Incremental cost-effectiveness ratio; PGT-A: preimplantation genetic testing for aneuploidy;ART: Assisted reproductive technology