Outcome variables | Predictor variables | Intervention Ward | Control Ward | ||||||
---|---|---|---|---|---|---|---|---|---|
Coefficient of determination | Estimation (SE) | 95% CI | P-value | Coefficient of determination | Estimation (SE) | 95% CI | P-value | ||
Omission/medication discrepancy | Intercept | 0.85 | 0.036 (0.014) | (0.008 to 0.064) | < 0.001 | 0.08 | 0.038 (0.010) | (0.019 to 0.058) | < 0.001 |
Time | 0.000 (0.001) | (−0.001 to 0.002) | 0.429 | 0.000 (0.000) | (−0.001 to 0.001) | 0.828 | |||
Intervention | 0.194 (0.031) | (0.134 to 0.254) | < 0.001 | −0.036 (0.022) | (−0.079 to 0.007) | 0.105 | |||
Time after intervention | 0.005 (0.004) | (−0.002 to 0.012) | 0.193 | 0.002 (0.003) | (−0.003 to 0.008) | 0.360 | |||
No indication | Intercept | 0.31 | 0.008 (0.002) | (0.004 to 0.011) | 0.000 | 0.39 | 0.003 (0.002) | (−0.001 to 0.007) | 0.186 |
Time | 0.000 (0.000) | (0.000 to 0.000) | 0.199 | 0.000 (0.000) | (0.000 to 0.000) | 0.931 | |||
Intervention | 0.004 (0.005) | (−0.006 to 0.014) | 0.475 | 0.025 (0.005) | (0.015 to 0.035) | < 0.001 | |||
Time after intervention | 0.001 (0.001) | (−0.001 to 0.002) | 0.333 | −0.002 (0.001) | (−0.003 to − 0.001) | 0.001 | |||
Duplication | Intercept | 0.18 | 0.017 (0.007) | (0.003 to 0.030) | 0.018 | 0.10 | 0.022 (0.006) | (0.011 to 0.033) | < 0.001 |
Time | 0.000 (0.000) | (0.000 to 0.001) | 0.589 | 0.000 (0.000) | (−0.001 to 0.000) | 0.221 | |||
Intervention | −0.005 (0.015) | (− 0.034 to 0.024) | 0.739 | 0.015 (0.012) | (−0.009 to 0.039) | 0.232 | |||
Time after intervention | 0.003 (0.002) | (−0.001 to 0.006) | 0.111 | 0.001 (0.001) | (−0.002 to 0.004) | 0.659 | |||
Allergy or contraindication | Intercept | 0.28 | 0.001 (0.002) | (−0.003 to 0.005) | 0.624 | 0.08 | 0.005 (0.005) | (−0.004 to 0.014) | 0.279 |
Time | 0.000 (0.000) | (0.000 to 0.000) | 0.025 | 0.000 (0.000) | (0.000 to 0.001) | 0.185 | |||
Intervention | 0.000 (0.006) | (−0.011 to 0.011) | 1.000 | −0.018 (0.01) | (−0.038 to 0.002) | 0.082 | |||
Time after intervention | 0.000 (0.001) | (−0.001 to 0.001) | 0.920 | 0.002 (0.001) | (−0.001 to 0.004) | 0.217 | |||
Drug- interaction | Intercept | 0.33 | 0.007 (0.007) | (− 0.006 to 0.020) | 0.304 | 0.02 | 0.016 (0.005) | (0.006 to 0.027) | 0.004 |
Time | 0.000 (0.000) | (0.000 to 0.001) | 0.346 | 0.000 (0.000) | (0.000 to 0.000) | 0.977 | |||
Intervention | 0.015 (0.015) | (−0.014 to 0.043) | 0.308 | 0.008 (0.012) | (−0.014 to 0.031) | 0.475 | |||
Time after intervention | 0.001 (0.002) | (−0.002 to 0.005) | 0.432 | −0.001 (0.001) | (−0.004 to 0.001) | 0.310 | |||
Inappropriate choice of drug | Intercept | 0.77 | 0.052 (0.016) | (0.020 to 0.083) | 0.002 | 0.00 | 0.046 (0.015) | (0.016 to 0.075) | 0.004 |
Time | 0.000 (0.001) | (−0.002 to 0.001) | 0.716 | 0.000 (0.001) | (−0.001 to 0.001) | 0.761 | |||
Intervention | 0.074 (0.035) | (0.006 to 0.143) | 0.039 | −0.01 (0.033) | (−0.074 to 0.055) | 0.773 | |||
Time after intervention | 0.020 (0.004) | (0.011 to 0.028) | < 0.001 | 0.000 (0.004) | (−0.008 to 0.008) | 0.994 | |||
Inappropriate dose/frequency | Intercept | 0.65 | 0.327 (0.030) | (0.268 to 0.386) | < 0.001 | 0.04 | 0.324 (0.036) | (0.254 to 0.394) | < 0.001 |
Time | −0.002 (0.001) | (− 0.004 to 0.001) | 0.214 | 0.001 (0.002) | (−0.002 to 0.004) | 0.579 | |||
Intervention | 0.301 (0.065) | (0.173 to 0.429) | < 0.001 | 0.061 (0.077) | (−0.091 to 0.213) | 0.433 | |||
Time after intervention | 0.005 (0.008) | (−0.011 to 0.02) | 0.544 | −0.007 (0.009) | (−0.025 to 0.011) | 0.453 | |||
Inappropriate route/formulation | Intercept | 0.75 | 0.015 (0.004) | (0.007 to 0.023) | 0.001 | 0.30 | 0.022 (0.006) | (0.010 to 0.033) | < 0.001 |
Time | 0.000 (0.000) | (0.000 to 0.001) | 0.287 | 0.000 (0.000) | (0.000 to 0.001) | 0.487 | |||
Intervention | 0.003 (0.011) | (−0.019 to 0.024) | 0.810 | 0.043 (0.016) | (0.012 to 0.074) | 0.010 | |||
Time after intervention | 0.010 (0.001) | (0.007 to 0.013) | < 0.001 | −0.005 (0.002) | (−0.009 to − 0.001) | 0.017 | |||
Typing error | Intercept | 0.60 | 0.139 (0.006) | (0.126 to 0.151) | < 0.001 | 0.11 | 0.108 (0.022) | (0.066 to 0.151) | < 0.001 |
Time | −0.001 (0.000) | (−0.002 to − 0.001) | < 0.001 | 0.001 (0.001) | (− 0.001 to 0.003) | 0.240 | |||
Intervention | 0.122 (0.022) | (0.079 to 0.166) | < 0.001 | −0.012 (0.047) | (−0.104 to 0.080) | 0.797 | |||
Time after intervention | −0.004 (0.003) | (−0.009 to 0.002) | 0.233 | 0.004 (0.006) | (−0.007 to 0.015) | 0.509 | |||
Inappropriate concentration/ rate of administration | Intercept | 0.41 | 0.048 (0.010) | (0.028 to 0.067) | < 0.001 | 0.13 | 0.012 (0.010) | (−0.007 to 0.032) | 0.224 |
Time | −0.001 (0.000) | (−0.001 to 0.000) | 0.121 | 0.001 (0.000) | (0.000 to 0.002) | 0.012 | |||
Intervention | 0.112 (0.021) | (0.070 to 0.154) | < 0.001 | −0.013 (0.022) | (−0.055 to 0.030) | 0.567 | |||
Time after intervention | −0.007 (0.003) | (−0.012 to − 0.002) | 0.008 | − 0.003 (0.003) | (− 0.008 to 0.002) | 0.247 | |||
Not-in-benefit package | Intercept | 0.84 | 0.073 (0.014) | (0.046 to 0.101) | < 0.001 | 0.22 | 0.074 (0.015) | (0.044 to 0.104) | < 0.001 |
Time | 0.001 (0.001) | (0.000 to 0.002) | 0.037 | 0.001 (0.001) | (−0.001 to 0.002) | 0.375 | |||
Intervention | 0.236 (0.038) | (0.161 to 0.311) | < 0.001 | −0.028 (0.038) | (−0.103 to 0.047) | 0.472 | |||
Time after intervention | 0.001 (0.005) | (−0.009 to 0.010) | 0.902 | 0.002 (0.005) | (−0.007 to 0.011) | 0.651 | |||
Monitor error | Intercept | 0.23 | 0.071 (0.022) | (0.028 to 0.113) | 0.002 | 0.06 | 0.059 (0.017) | (0.025 to 0.093) | 0.001 |
Time | 0.002 (0.001) | (0.000 to 0.004) | 0.028 | 0.001 (0.001) | (−0.001 to 0.002) | 0.325 | |||
Intervention | 0.018 (0.057) | (−0.094 to 0.130) | 0.752 | 0.031 (0.037) | (−0.041 to 0.104) | 0.403 | |||
Time after intervention | −0.006 (0.007) | (−0.020 to 0.008) | 0.410 | −0.005 (0.004) | (−0.014 to 0.004) | 0.290 | |||
Others | Intercept | 0.68 | 0.008 (0.008) | (−0.008 to 0.025) | 0.340 | 0.04 | 0.014 (0.006) | (0.001 to 0.026) | 0.038 |
Time | 0.000 (0.000) | (0.000 to 0.001) | 0.239 | 0.000 (0.000) | (0.000 to 0.001) | 0.587 | |||
Intervention | 0.013 (0.013) | (−0.012 to 0.038) | 0.315 | −0.015 (0.014) | (−0.042 to 0.013) | 0.306 | |||
Time after intervention | 0.006 (0.002) | (0.002 to 0.009) | 0.001 | 0.000 (0.002) | (−0.003 to 0.004) | 0.891 |