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Table 15 Description of Studies: Medically Unexplained Symptoms

From: A systematic review of economic analyses of psychological interventions and therapies in health-related settings

Authors, Year

Condition

CEA

CUA

Setting

N (participants)

Baseline Characteristics

Intervention/ comparator(s)

Effectiveness measure(s); cost measures (price year)

Perspective

Time horizon

Chernyak et al. 2014 [43*]

Medically unexplained symptoms

 

✓

Germany

Participants:

211

12 weekly sessions of psychodynamic interpersonal therapy (PIT), delivered by clinicians trained in psychotherapy, compared to enhanced medical care.

Intervention: 107

Control: 104

SF-36;

Healthcare

1 yr

Patients from 6 academic outpatient centres

Age in years (mean):

Intervention: 47.9;

Control: 48.0

Euros (2012)

Sex (% female):

Intervention: 67; Control: 72

Ethnicity (% white):

Not given

Schroder et al. 2017 [91*]

Medically unexplained symptoms

 

✓

Denmark;

N Participants:

120

9 modules of manualised group CBT, delivered by psychiatrists, versus enhanced usual care.

Intervention: 54

Control: 66

SF-36 converted to SF-6D utility scores;

Healthcare and societal

40mths

Hospital

Age in years (mean, SD):

Intervention: 35.4 (6.3)

Control: 36.2 (6.5)

Euros (2010 prices)

Sex (% female):

Intervention: 74;

Control: 83

Ethnicity (% white):

Not given

van Ravesteijn et al. 2013 [101*]

Medically unexplained symptoms

 

✓

Netherlands;

N Participants:

96

8 × 2.5 hr. group sessions of MBCT delivered by experienced mindfulness trainers, compared with enhanced usual care.

Intervention: 55

Control: 41

SF-36;

Healthcare and societal

12mths

Frequently attending patients in primary care

Age in years (mean, SD):

Intervention: 47.0 (11.3),

Control: 48.1 (12.3)

Euros (2010)

Sex (% female):

Intervention: 80.3;

Control: 67.9

Ethnicity (% white):

Not given

Visser et al. 2015 [103*]

Medically unexplained symptoms

 

✓

Netherlands;

N Participants:

162

cognitive-behavioural group training (2 hr. weekly sessions over 3mths) compared to a wait-list control group

Intervention: 84

Control: 78

SF-36;

Healthcare and societal

3 mths (12 month uncontrolled follow up;

costs, utilities & QALYs modelled over 4 years)

Outpatient clinics at general hospitals and a secondary community mental health service

Age in years (mean, SD):

Intervention: 46, Control: 42

Euros (2011)

Sex (% female):

Intervention: 80; Control: 82

Ethnicity (% white):

Not given