Table 11 Description of Studies: CHD

Ladapo et al. 2012 [63*]

Cardiovascular

✓

USA;

N Participants:

237

Intervention: Problem Solving Therapy and/or anti-depressants versus usual care.

Intervention: 80

TAU = 77

Nondepressed: 80

QALYs (SF-12/ SF 6D);

Healthcare

6mths

Hospital inpatient and outpatients in medical and mental health

Age in years (mean):

Intervention: 59 (10.6); TAU: 61 (10.6);

Nondepressed: 63 (10.3)

USD (price year not stated)

Sex (% female):

53

Ethnicity (% white):

49% Hispanic, and 19% Afro-American; no further details

Mejia et al. 2014 [75*]

Cardiovascular

✓

UK (England);

N Participants:

260

Treatment: 6 nurse led cognitive behaviourally informed self-management sessions consisting of a manual and further facilitated input. Control group: Usual care, the same manual, but with no further nurse led manual facilitation.

Self-management: 95

Usual care: 165

QALYs (EQ-5D-3L);

Healthcare

12mths

Hospital setting

Age in years (mean):

Intervention: 70 (12.5);

Control: 71 (10.9)

GBP 2008/2009 (basecase).

2011/2012 (sensitivity analysis).

Sex (% female):

28

Ethnicity (% white):

Not given

Tyrer et al. 2017 [95*]

Non Cardiac Chest Pain

✓

UK (England);

N Participants:

68

CBT for Chest Pain based on modification of CBT for Health Anxiety versus standard care.

Patients received between 4 and 10 sessions, with capacity to extend to 15 sessions if required.

CBT: 34

Standard care: 34

QALYs (EQ-5D);

Health and social care

1 year

Multi-centre

Age in years (mean, SD):

CBT: 48.91 (14.5); Standard care: 48.71 (13.5)

GBP (price year not stated)

Sex (% female):

CBT: 32 Standard care: 29

Ethnicity (% white):

CBT: 71 Standard care: 85