No | Authors, Year | Country | Study setting | Study population/ sample | Perspective | Intervention | Comparator | Discount rate |
---|---|---|---|---|---|---|---|---|
Anxiety & PTSD | ||||||||
 1 | Simon E. et al., 2013 [34] | The Netherlands | School setting, then referral if necessary | Children (aged 8–12), high and median anxious | Societal | 1. School-based screening child-focused intervention, 2. Screening and offering of a parent-focused intervention, 3. Screening and differentially offering a child- or parent focused intervention, based on parents’ anxious status | No intervention | Cost 4% |
 2 | Gospodarevskaya E. & Segal L., 2012 [26] | Australia | Health care setting | 10-year-old children who met either all or most of the PTSD diagnostic criteria | Health care system | 1. Cognitive behavioral therapy (TF-CBT) 2. TF-CBT combined with selective serotonin reuptake inhibitor (SSRI) 3. Non-directive counselling | No treatment | Both cost and effects 5% |
 3 | Mihalopoulos C. et al., 2015 [27] | Australia | Health care setting | Prevalent cases of PTSD estimated for the Australian population of 2012 children under 16 years | Health care system | Trauma-focused cognitive behavioural therapy (TF-CBT) in children | Current practice in Australia. | Both cost and effects 3% |
 4 | Shearer J. et al., 2018 [31] | UK | Hospital setting | Children aged 8–17 years, diagnosed with PTSD | Health care system | Cognitive therapy for PTSD (CT-PTSD) | Usual care | Both cost and effects 3.5% |
 5 | Mavranezouli I. et al., 2020 [32] | UK | National Health Service and personal social services in England | Children and young people (aged under 18 years) with clinically important PTSD symptoms | Health care system | 10 psychological interventions 1. Cognitive therapy for PTSD (TF-CBT) 2. Cohen TF-CBT 3. Narrative exposure therapy (TF-CBT) 4. Exposure/ prolonged exposure therapy (TF-CBT) 5. Group CBT (TF-CBT) 6. Eye movement desensitisation and reprocessing (EMDR) 7. Family therapy 8. Play therapy 9. Parent training 10. Supportive counselling | No treatment | Both cost and effects 3.5% |
Depression | ||||||||
 6 | Mihalopoulos C. et al., 2012 [28] | Australia | School setting | 11- to 17-year-old children and adolescents in the 2003 Australian population | Health care system | Population-level preventive intervention that screens children and adolescents for symptoms of depression in schools and the subsequent provision of a psychological intervention to those showing elevated signs of depression. | No intervention | Both cost and effects 3% |
 7 | Lee YY. et al., 2017 [29] | Australia | Primary and secondary schools | Youth aged 11–17 years in the 2013 Australian population. | health and education sector | 1) Universal prevention involving group-based psychological interventions delivered to all participating school students. 2) Indicated prevention involving group-based psychological interventions delivered to students with subthreshold depression. | No intervention | Both cost and effects 3% |
 8 | Ssegonja R. et al., 2020 [35] | Sweden | School setting | A hypothetical homogeneous cohort of adolescents at a start-age of 15 years with subsyndromal depression (SD) | Health care system and limited societal perspective | Group based cognitive behavioural therapy (GB-CBT) | No intervention | Both cost and effects 3% |
Anorexia nervosa | ||||||||
 9 | Byford S. et al., 2019 [36] | UK and Ireland | Community-based secondary or tertiary child and adolescent mental health services (CAMHS) | Hypothetical cohort of children aged 8–17 years in contact with CAMHS for a first episode of anorexia nervosa | Health care system | Community-based specialist eating disorders services | Generic CAMHS care | Not done as the follow up not more than 12 months. |
 10 | Le LK-D. et al., 2017 [30] | Australia | Youth aged 11–17 years in the 2013 Australian population. | The target population was 11–18 year olds with anorexia nervosa | Health care system | Family-based treatment (FBT) compared to adolescent-focused individual therapy (AFT) | No intervention | Both cost and effects 3% |
Other | ||||||||
 11 | Cottrell DJ. et al., 2018 [33] | UK | Child and Adolescent Mental Health Services (CAMHS) across three English regions. | Young people aged 11–17 years who had self-harmed at least twice presenting to CAMHS following self-harm. | Health care system | Family therapy (FT) delivered by trained and supervised family therapists (n = 415) | Treatment as usual (TAU) offered by local CAMHS following self-harm (n = 417) | Both cost and effects 3.5% |
 12 | Freriks RD. et al., 2019 [37] | USA | Health care setting | Children 7–10 years, participated in Multimodal Treatment Study of Children With ADHD in United States | Not explicitly stated. But mentioned as societal cost and outcome in the abstract and discussion sections. | Three major forms of ADHD treatment (medication management, behavioral treatment, and the combination) | Routine community care | Both cost and effects 3% |