Table 3 Quality of life values used in the modelling
From: Priorities among effective clinical preventive services in British Columbia, Canada
Health State (Definition or Duration) | QoL Reduction (Range) | Reference |
|---|---|---|
Taking medication for prevention | 0.0024 (0.00 – 0.0033) | |
Alcohol Use | ||
 Binge drinking | 0.123 (0.082 - 0.177) | |
 Hazardous alcohol use (3 to 4.5 drinks per day for males and 1.5 to 3 drinks per day for females) | 0.179 (0.121 - 0.252) | |
 Harmful alcohol use (> 4.5 drinks per day for males and > 3 drinks per day for females) | 0.304 (0.204 - 0.418) | |
Atopic dermatitis / eczema | 0.043 (0.026 – 0.065) | GBD |
Cancer – Breast | ||
 False-positive mammography result (4.7 days) | 0.013 | [104] |
 Diagnosis and treatment phase (3 months) | 0.288 (0.193 - 0.399) | GBD, [102] |
 Metastatic phase (17.7 months) | 0.451 (0.307 - 0.600) | |
 Remission | 0.049 (0.031 - 0.072) | |
Cancer – Cervical | ||
 False-positive Pap smear (10 months) | 0.046 | GBD |
 Diagnosis and treatment for CIN (20 months) | 0.066 | |
 Diagnosis and treatment phase for cancer (4.8 months) | 0.288 (0.193 - 0.399) | GBD, [105] |
 Metastatic phase (9.2 months) | 0.451 (0.307 - 0.600) | |
 Remission | 0.049 (0.031 - 0.072) | |
Cancer – Colorectal | ||
 Diagnosis and treatment phase (4 months) | 0.288 (0.193 - 0.399) | GBD |
 Metastatic phase (9.7 months) | 0.451 (0.307 - 0.600) | |
 Remission | 0.049 (0.031 - 0.072) | |
Cancer – Liver | ||
 Diagnosis and treatment phase (4 months) | 0.288 (0.193 - 0.399) | GBD |
 Metastatic phase (2.5 months) | 0.451 (0.307 - 0.600) | |
 Remission | 0.049 (0.031 - 0.072) | |
Cancer – Lung | ||
 Diagnosis and treatment phase (3.3 months) | 0.288 (0.193 - 0.399) | GBD |
 Metastatic phase (4.5 months) | 0.451 (0.307 - 0.600) | |
 Remission | 0.049 (0.031 - 0.072) | |
Cancer – Ovarian | ||
 Diagnosis and treatment phase (3.2 months) | 0.288 (0.193 - 0.399) | GBD |
 Metastatic phase (25.6 months) | 0.451 (0.307 - 0.600) | |
 Remission | 0.049 (0.031 - 0.072) | |
Cardiovascular Disease - myocardial infarction (1 month) | 0.100 (0.065 – 0.137) | GBD |
Cardiovascular Disease - stroke | 0.200 (0.134 - 0.265) | GBD, [106] |
Childhood asthma | 0.040 (0.024 – 0.060) | GBD, [107] |
Chronic pelvic pain (5 years) | 0.114 (0.078 - 0.159) | GBD, [79] |
Dental caries | ||
 Symptomatic dental caries | 0.010 (0.005 - 0.019) | GBD |
 Severe tooth loss | 0.067 (0.045 - 0.095) | |
Depression | ||
 Mild | 0.145 (0.099 - 0.209) | [108] |
 Moderate | 0.396 (0.267 - 0.531) | |
 Severe | 0.658 (0.477 - 0.807) | |
Diabetes – Type 2 | ||
 Uncomplicated | 0.049 (0.031 - 0.072) | GBD |
 Diabetic neuropathy | 0.133 (0.089 - 0.187) | |
Ectopic pregnancy (4 weeks) | 0.114 (0.078 - 0.159) | GBD, [79] |
End-stage renal disease | ||
 Chronic kidney disease | 0.104 (0.070 - 0.147) | GBD |
 On dialysis | 0.571 (0.398 - 0.725) | |
Fetal alcohol spectrum disorder | 0.50 (0.44 - 0.57) | [109] |
Fetal alcohol syndrome | 0.56 (0.48 - 0.63) | |
Gastrointestinal bleeding (28 days) | 0.265 | [110] |
Hepatitis C infection | ||
 Non-cirrhosis (fibrosis stage 0-3) | 0.088 (0.038 – 0.138) | |
 Compensated cirrhosis (fibrosis stage 4) | 0.138 (0.088 – 0.188) | |
 Decompensated cirrhosis | 0.188 | |
 Liver transplant (1st year) | 0.438 | |
 Liver transplant (subsequent years) | 0.163 | |
 On-treatment | 0.113 (0.063 – 0.163) | |
HIV/AIDS | ||
 Symptomatic HIV without anemia | 0.274 (0.184 - 0.377) | GBD |
 Symptomatic HIV with mild anemia | 0.277 (0.189 - 0.379) | |
 Symptomatic HIV with moderate anemia | 0.312 (0.217 - 0.418) | |
 Symptomatic HIV with severe anemia | 0.381 (0.269 - 0.505) | |
 AIDS with antiretroviral treatment (ART) without anemia | 0.078 (0.052 - 0.111) | |
 AIDS with ART with mild anemia | 0.081 (0.054 - 0.116) | |
 AIDS with ART with moderate anemia | 0.125 (0.085 - 0.176) | |
 AIDS with ART with severe anemia | 0.215 (0.148 - 0.295) | |
Infertility | ||
 Primary infertility | 0.008 (0.003 - 0.015) | GBD |
 Secondary infertility | 0.005 (0.002 - 0.011) | |
Intellectual disability | ||
 Borderline | 0.011 (0.005 - 0.020) | GBD |
 Mild | 0.043 (0.026 - 0.064) | |
 Moderate | 0.100 (0.066 - 0.142) | |
 Profound | 0.200 (0.133 - 0.283) | |
Obesity | ||
 Children / youth | 0.026 (0.017 – 0.036) | |
 Adults | 0.037 (0.024 – 0.049) | [115] |
Osteoporosis | ||
 Hip fracture (6 months) | 0.355 | [116] |
 Vertebral fracture (12 months) | 0.050 | [117] |
Chlamydial or gonococcal infection – mild | 0.006 (0.002 - 0.012) | GBD |
Spina bifida | ||
 Sacral lesion | 0.34 (0.06 – 0.62) | [118] |
 Lower lumbar lesion | 0.42 (0.22 – 0.62) | |
 Upper lumbar lesion | 0.52 (0.25 – 0.78) | |
Tobacco smoking | ||
 Light (< 10 cigarettes / day) | 0.031 (0.018 - 0.045) | [115] |
 Moderate (10-19 cigarettes / day) | 0.033 (0.019 - 0.047) | |
 Heavy (≥20 cigarettes / day) | 0.062 (0.042 - 0.082) | |
Vision deficits | ||
 Mild | 0.003 (0.001 - 0.007) | GBD |
 Moderate | 0.031 (0.019 - 0.049) | |
 Severe | 0.184 (0.125 - 0.258) | |
 Blindness | 0.187 (0.124 - 0.260) | |