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Table 4 Distribution and clinical manifestations of new / serious adverse drug reactions

From: Reevaluation of adverse drug reactions of psychiatric drugs under the chinese drug volume-based procurement policy

Drugs

New

Severe

Case

Ratio

(%)

Clinical manifestations

(Case)

Cases

Ratio

(%)

Clinical manifestations

(Case)

Olanzapine

3

2.31

Allergic dermatitis (1) / Menstruation occurs two years after menopause (1) / Blurred vision (1)

9

6.91

Abnormal liver function (2) / Excessive sedation (1) / Rash (1) / Orthostatic hypotension (1) / Bradycardia (1) / Allergic dermatitis (1) / Dyslipidemia (1) / Extrapyramidal reaction (1)

Risperidone

3

2.31

Dizziness (2) / Sinus tachycardia (1)

5

3.85

Leukopenia (1) / Sinus bradycardia (1) / Malignant syndrome (1) / Blurred vision (1) / Difficulty urinating (1)

Clozapine

2

1.54

Hypothyroidism (1) / Increased blood drug concentration (1)

6

4.62

Incomplete intestinal obstruction (1) / Epileptic seizures (1) / Sinus tachycardia (1) / Abnormal liver function (1) / Thrombocytopenia (1) / Increased blood drug concentration (1)

Quetiapine

0

0

 

6

4.62

Abnormal liver function (2) / Leukopenia (1) / Excessive sedation (1) / Dry mouth (1) / Lactation (1)

Total

8

6.16

 

26

20.00