Table 3 The organs/systems involved in adverse drug reactions and the clinical manifestations
Involved organs/systems | Case | Ratio (%) | Clinical manifestations (Case) |
|---|---|---|---|
Digestive system | 61 | 44.53 | Constipation (40) / Abnormal liver function (9) / Salivation (8) / Dry mouth (2) / Incomplete intestinal obstruction (1) / Dysphagia (1) |
Nervous system | 33 | 24.09 | Excessive sedation (10) / Extrapyramidal reactions (8) / Drowsiness (4) / Dizziness (3) / Epileptic seizures (2) / Akathisia (2) / Blurred vision (2) / Dry eyes (1) / Restlessness (1) |
Cardiovascular system | 12 | 8.75 | Sinus tachycardia (4) / Sinus bradycardia (3) / Lower blood pressure (3) / Prolonged Q-T interval (1) / Palpitation (1) |
Blood and lymphatic system | 10 | 7.30 | Leukopenia (6) / Thrombocytopenia (2) / Decreased albumin (1) / Increased blood drug concentration (1) |
Endocrine system | 7 | 5.11 | Hyperprolactinemia (4) / Hypothyroidism (1) / Menstruation occurs two years after menopause (1) / Lactation (1) |
Systemic reaction | 7 | 5.11 | Lower limb edema (5) / Malignant syndrome (1) / Asthenia (1) |
Metabolic and nutritional disorders | 3 | 2.19 | Dyslipidemia (2) / Hyperglycemia (1) |
Urinary and reproductive systems | 2 | 1.46 | Difficulty urinating (1) / Frequent urination (1) |
Skin and accessory organs | 2 | 1.46 | Allergic dermatitis (1) / Rash (1) |
Total | 137 | 100 |