Clinical variation in the organization of clinical pathways in esophagogastric cancer, a mixed method multiple case study

Luijten, J. C. H. B. M.; Vissers, P. A. J.; Brom, L.; de Bièvre, M.; Buijsen, J.; Rozema, T.; Mohammad, N. Haj; van Duijvendijk, P.; Kouwenhoven, E. A.; Eshuis, W. J.; Rosman, C.; Siersema, P. D.; van Laarhoven, H. W. M.; Verhoeven, R. H. A.; Nieuwenhuijzen, G. A. P.; Westerman, M. J.

doi:10.1186/s12913-022-07845-2

Table 3 Quantitative outcome parameters oesophageal and gastric cancer according to the probability of receiving treatment with curative intent

From: Clinical variation in the organization of clinical pathways in esophagogastric cancer, a mixed method multiple case study

	Oesophageal cancer probabiliy								Gastric cancer probability
	Low		Middle		High		p value low versus high	p value middle versus high	Low		Middle		High		p value low versus high	p value middle versus high
Total	477	100%	548	100%	625	100%			516		333		560
PET-CT	347	73%	425	78%	458	73%	0.84	0.09	103	20%	44	13%	114	21%	0.81	< 0.01
EUS	229	49%	266	49%	293	47%	0.71	0.57	70	14%	37	11%	69	13%	0.58	0.56
DLS	NA		NA		NA				91	18%	66	20%	94	17%	0.77	0.28
Prior to MDTM
Radiation oncologist	233	47%	263	48%	329	53%	0.053	0.11	9	2%	7	2%	12	2%	0.62	0.95
Medical oncologist	305	64%	324	59%	401	64%	0.94	0.08	293	58%	189	58%	316	58%	0.95	0.96
Surgeon	259	54%	301	55%	393	63%	< 0.01	< 0.01	311	61%	198	61%	374	69%	0.01	0.02
Multidisciplinary^b	193	40%	250	46%	310	50%	0.003	0.173	249	495	155	47%	266	49%	0.92	0.69
Geriatrician prior to MDTM	33	7%	24	4%	20	3%	< 0.01	0.29	56	11%	20	6%	66	12%	0.59	< 0.01
Geriatrician prior to MDTM according to age groups
< 70 years	7	58%	1	8%	4	33%	0.10*	0.22	2	29%	1	14%	4	57%	0.26	0.27*
70—74	14	52%	8	20%	5	19%	< 0.01	0.41	11	48%	4	17%	8	35%	0.37	0.23*
75—80	10	36%	10	36%	8	29%	0.31	0.58	20	39%	5	10%	26	51%	0.55	0.02
> 80	2	20%	5	50%	3	30%	0.35*	0.24*	23	38%	10	16%	28	46%	0.52	0.1
Number of patients treated with neoadjuvant therapy	184		263		316				171		125		192
Restaging CT	36	20%	71	27%	82	26%	< 0.01	0.7	115	67%	79	63%	115	60%	0.58	0.61
Restaging PET-CT	98	53%	88	33%	145	46%	0.45	< 0.01	5	3%	9	7%	10	5%	0.12	0.36

^*Fishers exact test
^bMultidisciplinary for esophageal cancer is defined as: radiation oncologist, medical oncologist and surgeon. For gastric cancer multidisciplinary is defined as medical oncologist and surgeon

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ISSN: 1472-6963

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