Table 1 Baseline characteristics of the patients who were screened for and diagnosed with primary aldosteronism (PA)
Median (IQR), no. (%) | ||
|---|---|---|
Characteristics | Screened PA | Confirmed PA |
(n = 688) | (n = 107) | |
Age, years | 63.3 (48.9, 78.5) | 63.7 (54.7, 75.3) |
Sex, Female | 406 (59.0%) | 78 (72.9%) |
Body mass index, kg/m2 | 25.3 (22.3, 29.0) | 23.6 (21.3, 26.2) |
Blood pressure, mmHg | ||
Systolic | 149 (135, 163) | 151.0 (139, 164) |
Diastolic | 89 (78, 98) | 90.0 (80, 98) |
Presentations | ||
Hypertension with hypokalemia | 298 (43.3%) | 98 (91.6%) |
Hypertension in the young | 175 (25.4%) | 1 (0.9%) |
Moderate to severe hypertension | 97 (14.1%) | 0 (0.0%) |
Hypertension with adrenal incidentaloma | 81 (11.8%) | 4 (3.7%) |
Resistant hypertension | 23 (3.2%) | 4 (3.7%) |
Unknown cause | 14 (2.0%) | 0 (0.0%) |
Serum potassium, mmol/l | 3.8 (3.3, 4.1) | 3.1 (2.7, 3.6) |
Numbers of antihypertensive agents | 1 (1, 2) | 2 (2, 3) |
Plasma aldosterone concentration, ng/dl | 11.5 (5.2, 28.7) | 56.6 (34.8, 91.8) |
Plasma renin activity ratio, ng/ ml·h | 1.2 (0.2, 4.6) | 0.07 (0.01, 0.23) |
Plasma aldosterone concentration to plasma renin activity ratio, ng/dl per ng/(ml·h) | 7.1 (2.5, 34.8) | 899.7 (219.4, 4155.0) |