Diagnoses | CT scans referred by GP (n=228 522) | CT scans referred by hospital (n=284 640) | Crude OR (95%CI) | P-value crude | aAdjusted OR (95% CI) | P-value adjusted |
---|---|---|---|---|---|---|
All cancer and selected non-cancer diagnoses | 80 525 (35.2) | 100 637 (35.4) | 1.00 (0.98 1.01) | 0.377 | 1.01 (1.00 1.03) | 0.046 |
All Cancers diagnoses | 20 926 (9.2) | 22 567 (7.9) | 1.17 (1.15 1.19) | <.0001 | 1.12 (1.09 1.14) | <.0001 |
Lung | 5 031 (2.2) | 3 831 (1.3) | 1.65 (1.58 1.72) | <.0001 | 1.62 (1.55 1.69) | <.0001 |
Breast | 2 846 (1.3) | 4 301 (1.5) | 0.82 (0.78 0.86) | <.0001 | 0.77 (0.73 0.81) | <.0001 |
Prostate | 2 541 (1.1) | 3 582 (1.3) | 0.88 (0.84 0.93) | <.0001 | 0.85 (0.81 0.90) | <.0001 |
Colon | 3 203 (1.4) | 3 364 (1.2) | 1.19 (1.13 1.25) | <.0001 | 1.11 (1.05 1.16) | 0.0001 |
Melanoma of skin | 778 (0.3) | 943 (0.3) | 1.03 (0.94 1.13) | 0.573 | 1.02 (0.92 1.13) | 0.7106 |
Bladder | 1 445 (0.6) | 977 (0.3) | 1.85 (1.71 2.01) | <.0001 | 1.80 (1.65 1.96) | <.0001 |
Brain, central nervous system | 477 (0.2) | 421 (0.2) | 1.42 (1.24 1.62) | <.0001 | 1.40 (1.22 1.60) | <.0001 |
Rectum and anus | 1 189 (0.5) | 1 691 (0.6) | 0.88 (0.81 0.94) | 0.0005 | 0.80 (0.74 0.86) | <.0001 |
Non-Hodgkin lymphoma | 905 (0.4) | 1 135 (0.4) | 0.99 (0.91 1.08) | 0.878 | 0.97 (0.88 1.06) | 0.4406 |
Pancreas | 1 006 (0.4) | 792 (0.3) | 1.59 (1.44 1.74) | <.0001 | 1.50 (1.36 1.65) | <.0001 |
Endometrium | 492 (0.2) | 567 (0.2) | 1.08 (0.96 1.22) | 0.2050 | 1.04 (0.92 1.18) | 0.5476 |
Kidney | 1 192 (0.5) | 1 072 (0.4) | 1.39 (1.28 1.51) | <.0001 | 1.37 (1.26 1.49) | <.0001 |
Ovary | 498 (0.2) | 508 (0.2) | 1.22 (1.08 1.39) | 0.0014 | 1.08 (0.95 1.23) | 0.2154 |
Stomach | 392 (0.2) | 441 (0.2) | 1.11 (0.97 1.27) | 0.1403 | 1.03 (0.90 1.19) | 0.6748 |
Selected non-cancer diagnoses | 66 463 (29.1) | 85 865 (30.2) | 0.95 (0.94 0.96) | <.0001 | 0.97 (0.96 0.99) | <.0001 |
Coronary heart disease | 7 519 (3.3) | 15 978 (5.6) | 0.572 (0.560.59) | <.0001 | 0.55 (0.54 0.57) | <.0001 |
Heart failure | 3 309 (1.5) | 6 762 (2.4) | 0.60 (0.58 0.63) | <.0001 | 0.64 (0.61 0.67) | <.0001 |
Peripheral vascular disease | 4 690 (2.1) | 6 890 (2.4) | 0.85 (0.81 0.88) | <.0001 | 0.84 (0.81 0.87) | <.0001 |
Chronic obstructive pulmonary disease | 8 666 (3.8) | 14 515 (5.1) | 0.73 (0.71 0.75) | <.0001 | 0.79 (0.77 0.81) | <.0001 |
Diabetes | 6 078 (2.7) | 8 134 (2.9) | 0.93 (0.90 0.96) | <.0001 | 0.96 (0.93 0.99) | 0.022 |
Liver disease | 2 353 (1.0) | 3 181 (1.1) | 0.92 (0.87 0.97) | 0.0026 | 1.00 (0.94 1.05) | 0.872 |
Thyroid disorders | 3 317 (1.5) | 4 073 (1.4) | 1.02 (0.97 1.06) | 0.539 | 1.03 (0.99 1.09) | 0.1701 |
Kidney disease | 3 618 (1.6) | 4 643 (1.6) | 0.97 (0.93 1.01) | 0.176 | 0.96 (0.92 1.01) | 0.096 |
Inflammatory bowel disease | 2 325 (1.0) | 2 817 (1.0) | 1.03 (0.97 1.09) | 0.321 | 1.06 (1.00 1.12) | 0.042 |
Ulcer | 1 939 (0.9) | 2 930 (1.0) | 0.82 (0.78 0.87) | <.0001 | 0.86 (0.81 0.92) | <.0001 |
Hemiplegia/stroke | 19 427(8.5) | 20 074 (7.1) | 1.23 (1.20 1.25) | <.0001 | 1.30 (1.27 1.33) | <.0001 |
Parkinson disease | 584 (0.3) | 726 (0.3) | 1.00 (0.90 1.12) | 0.9999 | 1.02 (0.91 1.14) | 0.791 |
Multiple sclerosis | 236 (0.1) | 233 (0.1) | 1.26 (1.06 1.52) | 0.011 | 1.43 (1.19 1.72) | 0.0002 |
Epilepsy | 2 063 (0.9) | 3 182 (1.1) | 0.81 (0.76 0.85) | <.0001 | 0.86 (0.81 0.91) | <.0001 |
Dementia | 7 894 (3.5) | 4 730 (1.7) | 2.12 (2.04 2.20) | <.0001 | 2.23 (2.15 2.32) | <.0001 |
Osteoporosis | 4 568 (2.0) | 7 332 (2.6) | 0.77 (0.74 0.80) | <.0001 | 0.70 (0.68 0.73) | <.0001 |
Rheumatoid and connective tissue disease | 3 020 (1.3) | 3 616 (1.3) | 1.04 (0.99 1.09) | 0.106 | 1.04 (0.99 1.09) | 0.145 |
HIV/AIDS | 50 (0.02) | 66 (0.02) | 0.94 (0.65 1.36) | 0.758 | 1.05 (0.72 1.54) | 0.786 |
Depression/ anxiety | 4 940 (2.1) | 6 381 (2.2) | 0.96 (0.93 1.00) | 0.053 | 1.06 (1.02 1.10) | 0.0042 |
Psychotic diseases | 679 (0.3) | 1 427 (0.5) | 0.59 (0.54 0.65) | <.0001 | 0.70 (0.63 0.77) | <.0001 |