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Table 4 DTRPs identified and resolved by pharmacists in a 45-year-old type 2 diabetes and hypertensive SP.

From: Drug therapy-related problem management in Nigeria community pharmacy – process evaluation with simulated patient

Classification and types of DTRPs

Identified

n (%)

Not identified

n (%)

Drug therapy is used for an avoidable adverse drug reaction/side effects associated with another medication

 Coflin Lintus® possibly for cough associated with lisinopril.

4 (11.1)

32 (88.9)

Adverse drug reaction (A drug interaction causes an undesirable reaction that is not dose-related)

 Diclofenac + lisinopril decreases renal functiona

3 (8.3)

33 (91.7)

Dose too high (The dose too high for the patient)

 Glibenclamide 10 mg taken twice daily because of duplicate product.

31 (86.1)

5 (13.9)

Action taken to investigate DRP

Action taken

n (%)

Action not taken

n (%)

 Checked for drug interaction.

2 (5.6)

34 (94.4)

 Asked for clarification concerning the medicines.

32 (88.9)

4 (11.1)

 Probe the patient further about other symptoms of hypoglycaemia e.g., tremor, increased heart rate

21 (58.3)

15 (41.7)

Recommendations made to resolve the DTRPs

Recommendation made

n (%)

Recommendation not made

n (%)

 Suggested the stoppage of diclofenac tablets.

6 (16.7)

30 (83.3)

 Suggested the discontinuation of one of the glibenclamide brand.

32 (88.9)

4 (11.1)

 Suggested the patient see the physician for a possible replacement for lisinopril since the patient experienced episodes of uncomfortable dry cough.

4 (11.1)

32 (88.9)

 Suggested the discontinuation of Coflin Lintus®.

3 (8.3)

33 (91.7)

  1. DTRPs Drug therapy-related problems, n number of pharmacists, aSerious - Avoid or Use alternative, SP simulated patient.
  2. Coflin Lintus® – contain Chlorpheniramine maleate, Ammonium Chloride, Sodium citrate, Menthol and Ephedrine hydrochloride).