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Table 4 Drugs that cause observed adverse drug events

From: Clinical pharmacist assessment of drug-related problems among intensive care unit patients in a Turkish university hospital

Patients experiencing adverse drug reactions (%)

32 (21.19)

Cumulative incidence (ADE/patient)

0.23

Incidence density rate (ADE/1000 patient-days)

15.45

Adverse drug events detected

35

Drug-induced thrombocytopenia

6 (17.14%)

Piperacillin tazobactam

3 (8.57%)

Linezolid

2 (5.71%)

Heparin

1 (2.85%)

Nefrotoxicity

17 (48.57%)

Colistin

16 (45.71)

Apixaban

1 (2.85%)

Increase in liver enzymes

3 (8.57%)

Tigecycline

2 (5.71%)

Meropenem

1 (2.85%)

Electrolyte disorder (K + , Na +)

6 (17.14%)

Trimethoprim-sulfamethoxazole induced hyperkalemia

3 (8.57%)

Heparin induced hyponatremia

1 (2.85%)

Carbamazepine induced hyponatremia

1 (2.85%)

Escitalopram-induced hyponatremia

1 (2.85%)

Other

3 (8.57%)

Ciprofloxacin-associated seizures

1 (2.85%)

Midazolam over-sedation

1 (2.85%)

Metformin induced lactic acidosis

1 (2.85%)