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Table 1 Cost components

From: Economic impact of switching from partially combined vaccine “Pentaxim® and hepatitis B” to fully combined vaccine “Hexaxim®” in the Malaysian National Immunization Program

Cost component

Formula

Swab

Number of swabs used per dose of vaccine × swab price per piece

Syringe

Number of syringes per dose of vaccine × price of one syringe × syringes wastage factor

Needle

Number of needles per dose of vaccine × price of one needle × needles wastage factor

Safety box

(Syringe volume × no. of syringes per dose of vaccine) + (needle volume × no. of needles per dose of vaccine) + (vaccine vial volume × no. of vials per dose of vaccine) × (price of empty safety box)/actual safety box volume (mL) (2/3 of safety box gross volume)

Hazardous waste disposal

(Empty syringe weight × no. of syringes disposed per dose of vaccine) + needle weight × no. of needles per dose of vaccine) + (empty vaccine vial weight × no. of empty vials per dose of vaccine)/1000 × hazardous waste disposal price per 1000 g

Vaccine wastage

Purchase price of vaccine per dose × vaccine wastage factor

Cold chain: refrigerator

Vaccine package volume per dose (mL) × (refrigerator electricity expenditure per day × electricity price per kWh/refrigerator vaccine storage capacity (mL))

Cold chain: cold box

(Refrigerator or freezer electricity expenditure kWh × electricity price per kWh/freezer gross volume (mL)) × (ice pack total volume per cold box × vaccine volume per dose/cold box volume (mL))

Administration time

Monthly specific nurse salary (basic salary)/working hours per month/3600 × time (s) to administer one dose of vaccine

Transportation

Cost of transportation caregivers have to pay to and from the primary healthcare center per visit

Loss of productivity

Caregiver’s monthly salary/26 × time absent from work due to vaccination (days)