Fig. 1

PRISMA flow chart for the global search with regional-level outcomes. The search strategies returned 1432 records, 929 of which were duplicates. After screening the titles and abstracts of the remaining 503 references, a further 466 were excluded. The full texts of 37 articles were assessed for eligibility, of which 13 were found eligible and included in the analysis. Of the full-text articles assessed, 29 were excluded for the following reasons: No children between 1 and 12 years (3); No cost study as objective (4); Cost study but not indirect costs (9); No results by age group (7); No SSTIs as primary disease (3); and Review (3)