Variable name | Description | Mean | Standard deviation | Distribution type | Parameter 1 (alpha) | Parameter 2 (beta) |
---|---|---|---|---|---|---|
Probabilities of events | ||||||
 pes | Probability of esophageal stenosis | 0.0476 | 0.0005 | Beta | 4 | 80 |
 phem | Probability of hemorrhage | 0.0243 | 0.0001 | Beta | 6 | 241 |
 pho_adj | Probability of hospital readmission after adjuvant | 0.1731 | 0.0027 | Beta | 9 | 43 |
 pho_s | Probability of hospital readmission (TORS or TLM) | 0.0333 | 0.0010 | Beta | 1 | 29 |
 plg | Probability of long-term gastrostomy (1 year) after adjuvant treatment | 0.0500 | 0.0003 | Beta | 9 | 171 |
 plt | Probability of long-term tracheostomy (1 year) | 0.0226 | 0.0001 | Beta | 4 | 173 |
 psg | Probability of short-term (6 months) gastrostomy (TORS or TLM) | 0.0144 | 0.0001 | Beta | 2 | 137 |
 psg_adj | Probability of short-term (6 months) gastrostomy after adjuvant | 0.2991 | 0.0019 | Beta | 32 | 75 |
 por | Probability of osteoradionecrosis | 0.0265 | 0.0002 | Beta | 4 | 147 |
 ppf | Probability of pharyngocutaneous fistula | 0.0253 | 0.0001 | Beta | 10 | 385 |
 pTLMAlone | Probability of TLM alone | 0.4085 | 0.0007 | Beta | 134 | 194 |
 pTorsAlone | Probability of TORS alone | 0.3740 | 0.0001 | Beta | 824 | 1379 |
 pCRT_TLM | Probability of adjuvant CRT (TLM) | 0.6289 | 0.0012 | Beta | 122 | 72 |
 pCRT_tors | Probability of adjuvant CRT (TORS) | 0.5272 | 0.0002 | Beta | 727 | 652 |
 pRT_TLM | Probability of adjuvant RT (TLM) | 0.3711 | 0.0012 | Beta | 72 | 122 |
 pRT_tors | Probability of adjuvant RT (TORS) | 0.4728 | 0.0002 | Beta | 652 | 727 |
 plra | Probability of local or regional recurrence (first 2 years) | 0.0064 | 0.0000 | Beta | 11 | 1715 |
 prra | Probability of regional recurrence (first 2 years) | 0.0064 | 0.0000 | Beta | 11 | 1715 |
 pdra | Probability of distant recurrence (first 2 years) | 0.0038 | 0.0000 | Beta | 11 | 2900 |
Costs (CHF) | ||||||
 cTORS | Cost of TORS | 14,739 | 869.31 | Gamma | 287.4635 | 0.0195 |
 cTLM | Cost of TLM | 12,671 | 516.23 | Gamma | 602.4698 | 0.0475 |
 cCRT | Cost of adjuvant CRT | 33,911 | 2079.08 | Gamma | 266.0350 | 0.0078 |
 cRT | Cost of adjuvant RT | 27,962 | 1714.35 | Gamma | 266.0342 | 0.0095 |
 cES | Cost of esophageal stenosis | 2362 | 410.65 | Gamma | 33.0832 | 0.0140 |
 cGAST | Cost of gastrostomy | 4332 | 410.65 | Gamma | 111.2820 | 0.0257 |
 cHR_adj | Cost of hospital readmission (for adjuvant) | 10,097 | 619.05 | Gamma | 266.0342 | 0.0263 |
 cHR_s | Cost of hospital readmission (TORS or TLM) | 8203 | 803.41 | Gamma | 104.2498 | 0.0127 |
 cORN | Cost of osteoradionecrosis | 32,111 | 1077.71 | Gamma | 887.7769 | 0.0276 |
 cPF | Cost of pharyngocutaneous fistula | 82,892 | 333.96 | Gamma | 61,609.3654 | 0.7432 |
 cPH | Cost of hemorrhage (from surgical site) | 4469 | 415.50 | Gamma | 115.6865 | 0.0259 |
 cTRACH | Cost of tracheostomy | 11,688 | 612.67 | Gamma | 363.9366 | 0.0311 |
 cREM | Cost of remission 0–2 y | 168.5 | 9.68 | Gamma | 303.2588 | 1.7998 |
 c2REM | Cost of remission 2–5 y | 60 | 9.68 | Gamma | 38.4518 | 0.6409 |
 cPC | Cost of palliative care | 4137 | 367.86 | Gamma | 126.4754 | 0.0306 |
 cRR | Cost of regional recurrence | 7047 | 464.24 | Gamma | 230.4227 | 0.0327 |
 cLR_chemorad | Cost of local recurrence (chemoradiation) | 34,041 | 2079.08 | Gamma | 268.0786 | 0.0079 |
 cLR_s | Cost of local recurrence (surgical resection) | 40,513 | 2050.27 | Gamma | 390.4511 | 0.0096 |
 cDM | Cost of distant metastasis | 4137 | 367.86 | Gamma | 126.4754 | 0.0306 |
 cPanendo | Cost of panendoscopy | 388 | 23.79 | Gamma | 266.0337 | 0.6857 |
Utilities | ||||||
 uSURG | Utility coefficient of TORS or TLM | 0.902 | 0.203 | Beta | 1.0328 | 0.1122 |
 uRT | Utility coefficient of adjuvant RT | 0.850 | 0.275 | Beta | 0.5831 | 0.1029 |
 uCRT | Utility coefficient of adjuvant CRT | 0.794 | 0.317 | Beta | 0.4984 | 0.1293 |
 uHR | Utility coefficient of hospital readmission | 0.954 | 0.140 | Beta | 1.1820 | 0.0570 |
 uPF | Utility coefficient of pharyngocutaneous fistula | 0.932 | 0.194 | Beta | 0.6374 | 0.0465 |
 uPH | Utility coefficient of postoperative hemorrhage | 0.910 | 0.203 | Beta | 0.8986 | 0.0889 |
 Ug | Utility coefficient of gastrostomy | 0.916 | 0.209 | Beta | 0.6975 | 0.0640 |
 Ult | Utility coefficient of long-term tracheostomy | 0.852 | 0.271 | Beta | 0.6109 | 0.1061 |
 ues | Utility coefficient of esophageal stenosis | 0.826 | 0.284 | Beta | 0.6459 | 0.1361 |
 uORN | Utility coefficient of osteoradionecrosis | 0.791 | 0.302 | Beta | 0.6428 | 0.1698 |
 urem | Utility coefficient of remission after surgery and adjuvant | 0.980 | 0.099 | Beta | 0.7702 | 0.0346 |
 uremonlysurg | Utility coefficient of remission after TORS or TLM alone | 0.957 | 0.151 | Beta | 0.9798 | 0.0200 |
 ureg | Utility coefficient of regional recurrence | 0.859 | 0.283 | Beta | 0.4401 | 0.0722 |
 ulocxrt | Utility coefficient of local recurrence, RT | 0.771 | 0.302 | Beta | 0.7216 | 0.2143 |
 uloc | Utility coefficient of local recurrence, requiring surgery | 0.755 | 0.316 | Beta | 0.6436 | 0.2088 |
 udist | Utility coefficient of distant recurrence | 0.213 | 0.336 | Beta | 0.2262 | 0.5106 |
 upall | Utility coefficient of palliative care | 0.307 | 0.350 | Beta | 0.1033 | 0.3816 |