Fig. 1
From: Effects of the cefazolin shortage on the sales, cost, and appropriate use of other antimicrobials
Process in the production of cefazolin in the company of supply disruption. Manufacturer provides TAT to Factory A and B. Factory A and B synthesize CEZ, then Factory C productizes it. Foreign body inclusion was found in Factory A, and the factory stopped working. Thereafter, the outage of TAA material occurred in Manufacturer. These events caused a short of materials in Factory C, and resulted in a cease of cefazolin production. Abbreviation: TAA, Tetrazole-Acetic Acid. CEZ, Cefazolin