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Table 3 Summary of parameters

From: Patient-specific and healthcare real-world costs of atrial fibrillation in individuals treated with direct oral anticoagulant agents or warfarin

Parameter

Description of parameters

Value

Fixed parameters

tm

Time loss associated with INR monitoring

0.5 h

ta

Parking time for car or service time for taxi

0.083 h

cx

Daily cost of anticoagulant medicine for patient

Warfarin = € 0.08, DOACs = € 0.95–1.00

vp

Cost of primary healthcare visits for patient

€ 11.4 or € 20.6

 vs

Cost of specialised healthcare visits for patient

€ 41.2

dp

Cost of primary healthcare inpatient ward

€ 48.9

ds

Cost of specialised healthcare inpatient ward

€ 48.9

oc

Operation cost of car per kilometre

€ 0.43 / km

ot

Operation cost of taxi per kilometre

€ 1.59 / km

fb

Public transport fare

€ 2.00, 3.80 or 5.00

ft

Fixed charge for taxi

€ 5.9

s

Size of patient group

Warfarin = 3171, DOAC = 829

dh

Daily medicine cost for healthcare

Warfarin = € 0.05, DOACs = € 1.76 or 1.87

is

Cost of INR monitoring for healthcare per visits

€ 31 (blood test + healthcare personnel cost)

pa

Patient’s hourly gross wage coefficient

Working time is valued as 100% (age < =65) and leisure time as 35% of the hourly wage (age > 65)

Real-world data parameters

m

INR monitoring count

Based on EHR

ep

Cost of primary care visits for healthcare

Based on EHR

es

Cost of specialised healthcare visits for healthcare

Based on EHR

wp

Cost of inpatient ward for primary care

Based on EHR

ws

Cost of inpatient ward for specialised healthcare

Based on EHR

ct

Patient’s time cost per hour

From Zip code area income data

tt

Total travelling time

Calculated using network analysis

d

Distance of journey

Calculated using network analysis

tj

Travel time of journey

Calculated using network analysis

ce

Travel cost for ambulance

Kela database

k

Cost of travel reimbursement for healthcare

Kela database