Table 2 Baseline characteristics of caregivers and caregiver controls by subgroup after matching
Characteristics at index date | Breast Cancer Caregiver (N = 13,174) | Breast Cancer Caregiver Control (N = 178,966) | Colorectal Cancer Caregiver (N = 7,128) | Colorectal Cancer Caregiver Control (N = 235,282) |
Sex, n (%) | ||||
Female | 245 (1.9) | 3,293 (1.8) | 4,319 (60.6) | 142,523 (60.6) |
Male | 12,929 (98.1) | 175,673 (98.2) | 2,809 (39.4) | 92,759 (39.4) |
Age at index, mean (standard deviation, SD) years | 53.9 (10.7) | 53.6 (11.1) | 55.8 (11.4) | 55.2 (11.6) |
Health care payer type, n (%) | ||||
Commercial | 11,475 (87.1) | 155,967 (87.1) | 5,806 (81.5) | 191,426 (81.4) |
Medicare | 1,699 (12.9) | 22,999 (12.9) | 1,322 (18.5) | 43,856 (18.6) |
Health care plan type, n (%) | ||||
Capitated | 1,600 (12.1) | 25,483 (14.2) | 782 (11.0) | 33,376 (14.2) |
Fee for Service | 11,259 (85.5) | 149,054 (83.3) | 6,197 (86.9) | 196,300 (83.4) |
Unknown/Missing | 315 (2.4) | 4,429 (2.5) | 149 (2.1) | 5,606 (2.4) |
US geographic region, n (%) | ||||
North Central | 3,422 (26.0) | 47,198 (26.4) | 1,962 (27.5) | 64,582 (27.4) |
North East | 2,644 (20.1) | 31,165 (17.4) | 1,469 (20.6) | 41,528 (17.7) |
South | 4,616 (35.0) | 62,885 (35.1) | 2,595 (36.4) | 80,100 (34.0) |
West | 2,402 (18.2) | 35,832 (20.0) | 1,040 (14.6) | 46,581 (19.8) |
Unknown/Missing | 90 (0.7) | 1,886 (1.1) | 62 (0.9) | 2,491 (1.1) |
Employment status of primary policy holder, n (%) | ||||
Employed | 5,232 (39.7) | 64,913 (36.3) | 2,033 (28.5) | 57,883 (24.6) |
Not Employed | 1,671 (12.7) | 20,771 (11.6) | 823 (11.5) | 23,952 (10.2) |
Unknown/missing | 6,271 (47.6) | 93,282 (52.1) | 4,272 (59.9) | 153,447 (65.2) |
Charlson Comorbidity Indexa, mean (SD) | 0.3 (0.9) | 0.4 (0.9) | 0.4 (0.9) | 0.4 (0.9) |
Number of unique medications, mean (SD) | 3.5 (4.0) | 3.8 (4.2) | 4.2 (4.4) | 4.5 (4.6) |
Duration of follow up, median (interquartile range, IQR) months | 29.3 (5.9-108.1) | 22.1 (4.9-108.1) | 25.2 (5.9-107.5) | 22.4 (4.9-108.1) |
Characteristics at index date | Gastric Cancer Caregiver (N = 1,308) | Gastric Cancer Caregiver Control (N = 214,232) | Lung Cancer Caregiver (N = 9,600) | Lung Cancer Caregiver Control (N = 275,227) |
Sex, n (%) | ||||
Female | 974 (74.5) | 159,880 (74.6) | 5,484 (57.1) | 157,193 (57.1) |
Male | 334 (25.5) | 54,352 (25.4) | 4,116 (42.9) | 118,034 (42.9) |
Age at index, mean (SD) years | 57.1 (10.6) | 56.6 (11.0) | 60.7 (10.4) | 60.2 (10.6) |
Health care payer type, n (%) | ||||
Commercial | 1,037 (79.3) | 170,402 (79.5) | 6,554 (68.3) | 189,009 (68.7) |
Medicare | 271 (20.7) | 43,830 (20.5) | 3,046 (31.7) | 86,218 (31.3) |
Health care plan type, n (%) | ||||
Capitated | 145 (11.1) | 30,865 (14.4) | 944 (9.8) | 39,404 (14.3) |
Fee for Service | 1,130 (86.4) | 178,315 (83.2) | 8,457 (88.1) | 229,759 (83.5) |
Unknown/Missing | 33 (2.5) | 5,052 (2.4) | 199 (2.1) | 6,064 (2.2) |
US geographic region, n (%) | ||||
North Central | 362 (27.7) | 59,756 (27.9) | 3,029 (31.6) | 80,068 (29.1) |
North East | 312 (23.9) | 38,081 (17.8) | 2,140 (22.3) | 49,598 (18.0) |
South | 431 (33.0) | 71,763 (33.5) | 3,173 (33.1) | 88,974 (32.3) |
West | 195 (14.9) | 42,400 (19.8) | 1,172 (12.2) | 54,024 (19.6) |
Unknown/Missing | 8 (0.6) | 2,232 (1.0) | 86 (0.9) | 2,563 (0.9) |
Employment status of primary policy holder, n (%) | ||||
Employed | 387 (29.6) | 47,195 (22.0) | 2,575 (26.8) | 56,683 (20.6) |
Not Employed | 188 (14.4) | 20,564 (9.6) | 2,146 (22.4) | 44,434 (16.1) |
Unknown/missing | 733 (56.0) | 146,473 (68.4) | 4,879 (50.8) | 174,110 (63.3) |
Charlson Comorbidity Indexa, mean (SD) | 0.4 (1.0) | 0.4 (0.9) | 0.5 (1.0) | 0.5 (1.1) |
Number of unique medications, mean (SD) | 4.7 (4.9) | 4.7 (4.7) | 5.0 (4.8) | 5.0 (4.8) |
Duration of follow up, median (IQR) days | 21.2 (6.0-107.5) | 22.7 (5.9-108.1) | 22.7 (5.9-106.8) | 22.7 (5.9–108.0) |
Characteristics at index date | Sarcoma Caregiver (N = 907) | Sarcoma Caregiver Control (N = 142,992) | Male Cancer Patient Caregiver (N = 29,841) | Male Cancer Patient Caregiver Control (N = 213,204) |
Sex, n (%) | ||||
Female | 507 (55.9) | 79,985 (55.9) | 29,655 (99.4) | 211,871 (99.4) |
Male | 400 (44.1) | 63,007 (44.1) | 186 (0.6) | 1,333 (0.6) |
Age at index, mean (SD) years | 53.9 (11.9) | 53.6 (12.0) | 57.4 (11.3) | 56.8 (11.4) |
Health care payer type, n (%) | ||||
Commercial | 756 (83.4) | 119,728 (83.7) | 22,960 (76.9) | 164,126 (77.0) |
Medicare | 151 (16.6) | 23,264 (16.3) | 6,881 (23.1) | 49,078 (23.0) |
Health care plan type, n (%) | ||||
Capitated | 86 (9.5) | 20,439 (14.3) | 3,411 (11.4) | 30,755 (14.4) |
Fee for Service | 804 (88.6) | 119,208 (83.4) | 25,760 (86.3) | 177,594 (83.3) |
Unknown/Missing | 17 (1.9) | 3,345 (2.3) | 670 (2.2) | 4,855 (2.3) |
US geographic region, n (%) | ||||
North Central | 224 (24.7) | 38,667 (27.0) | 8,130 (27.2) | 60,258 (28.3) |
North East | 189 (20.8) | 25,078 (17.5) | 6,753 (22.6) | 38,003 (17.8) |
South | 312 (34.4) | 49,362 (34.5) | 10,164 (34.1) | 70,704 (33.2) |
West | 173 (19.1) | 28,429 (19.9) | 4,564 (15.3) | 42,075 (19.7) |
Unknown/Missing | 9 (1.0) | 1,456 (1.0) | 230 (0.8) | 2,164 (1.0) |
Employment status of primary policy holder, n (%) | ||||
Employed | 297 (32.7) | 37,685 (26.4) | 6,912 (23.2) | 38,304 (18.0) |
Not Employed | 100 (11.0) | 13,557 (9.5) | 3,033 (10.2) | 15,308 (7.2) |
Unknown/missing | 510 (56.2) | 91,750 (64.2) | 19,896 (66.7) | 159,592 (74.9) |
Charlson Comorbidity Indexa, mean (SD) | 0.3 (0.7) | 0.4 (0.9) | 0.4 (0.9) | 0.4 (0.9) |
Number of unique medications, mean (SD) | 4.1 (4.2) | 4.3 (4.5) | 4.9 (4.8) | 4.9 (4.8) |
Duration of follow up, median (IQR) months | 23.0 (6.0-103.4) | 22.3 (5.9–108.0) | 23.4 (5.9-107.9) | 22.8 (5.9–108.0) |
Characteristics at index date | Female Cancer Patient Caregiver (N = 33,052) | Female Cancer Patient Caregiver Control (N = 235,973) | Same-sex Caregiver (N = 458) | Same-sex Caregiver Control (N = 3,243) |
Sex, n (%) | ||||
Female | 272 (0.8) | 1,910 (0.8) | 272 (59.4) | 1,910 (58.9) |
Male | 32,780 (99.2) | 234,063 (99.2) | 186 (40.6) | 1,333 (41.1) |
Age at index, mean (SD) years | 56.5 (11.6) | 56.1 (11.8) | 52.0 (9.6) | 51.7 (9.9) |
Health care payer type, n (%) | ||||
Commercial | 26,243 (79.4) | 187,906 (79.6) | 423 (92.4) | 2,994 (92.3) |
Medicare | 6,809 (20.6) | 48,067 (20.4) | 35 (7.6) | 249 (7.7) |
Health care plan type, n (%) | ||||
Capitated | 3,845 (11.6) | 33,482 (14.2) | 116 (25.3) | 817 (25.2) |
Fee for Service | 28,489 (86.2) | 196,868 (83.4) | 337 (73.6) | 2,381 (73.4) |
Unknown/Missing | 718 (2.2) | 5,623 (2.4) | 5 (1.1) | 45 (1.4) |
US geographic region, n (%) | ||||
North Central | 9,046 (27.4) | 64,494 (27.3) | 59 (12.9) | 530 (16.3) |
North East | 7,108 (21.5) | 41,545 (17.6) | 108 (23.6) | 578 (17.8) |
South | 11,090 (33.6) | 80,783 (34.2) | 146 (31.9) | 994 (30.7) |
West | 5,555 (16.8) | 46,801 (19.8) | 124 (27.1) | 1,010 (31.1) |
Unknown/Missing | 253 (0.8) | 2,350 (1.0) | 21 (4.6) | 131 (4.0) |
Employment status of primary policy holder, n (%) | ||||
Employed | 12,192 (36.9) | 77,670 (32.9) | 194 (42.4) | 1,129 (34.8) |
Not Employed | 6,395 (19.3) | 39,633 (16.8) | 50 (10.9) | 214 (6.6) |
Unknown/missing | 14,465 (43.8) | 118,670 (50.3) | 214 (46.7) | 1,900 (58.6) |
Charlson Comorbidity Indexa, mean (SD) | 0.4 (1.0) | 0.5 (1.0) | 0.7 (1.7) | 0.6 (1.5) |
Number of unique medications, mean (SD) | 3.9 (4.2) | 4.1 (4.3) | 4.6 (4.8) | 4.8 (4.8) |
Duration of follow up, median (IQR) months | 28.1 (5.9–108.0) | 22.1 (4.9-108.1) | 26.0 (6.1-106.4) | 21.6 (6.0-108.0) |