Table 1 Baseline characteristics of the patient/patient control and caregiver/caregiver controls after matching
Characteristics at index date | Cancer Patient (N = 62,893) | Patient control (N = 449,177) | P-value | Caregiver (N = 62,893) | Caregiver Control (N = 449,177) | P-value |
|---|---|---|---|---|---|---|
Sex, n (%) | ||||||
Female | 33,052 (52.6) | 235,973 (52.5) | 0.93 | 29,927 (47.6) | 213,781 (47.6) | 0.96 |
Male | 29,841 (47.4) | 213,204 (47.5) | 32,966 (52.4) | 235,396 (52.4) | ||
Age at index, mean (standard deviation, SD) years | 57.7 (11.5) | 56.8 (11.8) | < 0.0001 | 56.9 (11.5) | 56.4 (11.6) | < 0.0001 |
Age categories, n (%) | ||||||
Age < 40 years | 3,873 (6.2) | 27,653 (6.2) | 1.0 | 4,136 (6.6) | 29,585 (6.6) | 1.0 |
40 ≤ Age < 55 | 20,006 (31.8) | 142,900 (31.8) | 21,548 (34.3) | 153,882 (34.3) | ||
55 ≤ Age < 65 | 24,363 (38.7) | 174,112 (38.8) | 23,735 (37.7) | 169,429 (37.7) | ||
Age ≥ 65 | 14,651 (23.3) | 104,512 (23.3) | 13,474 (21.4) | 96,281 (21.4) | ||
Health care payer type, n (%) | ||||||
Commercial | 48,042 (76.4) | 343,924 (76.6) | 0.32 | 49,203 (78.2) | 352,032 (78.4) | 0.43 |
Medicare | 14,851 (23.6) | 105,253 (23.4) | 13,690 (21.8) | 97,145 (21.6) | ||
Health care plan type, n (%) | ||||||
Capitated | 7,256 (11.5) | 64,165 (14.3) | < 0.0001 | 7,256 (11.5) | 64,237 (14.3) | < 0.0001 |
Fee for Service | 54,242 (86.2) | 374,538 (83.4) | 54,249 (86.3) | 374,462 (83.4) | ||
Unknown/Missing | 1,395 (2.2) | 10,474 (2.3) | 1,388 (2.2) | 10,478 (2.3) | ||
US geographic region, n (%) | ||||||
North Central | 17,175 (27.3) | 124,743 (27.8) | < 0.0001 | 17,176 (27.3) | 124,752 (27.8) | < 0.0001 |
North East | 13,857 (22.0) | 79,572 (17.7) | 13,861 (22.0) | 79,548 (17.7) | ||
South | 21,252 (33.8) | 151,522 (33.7) | 21,254 (33.8) | 151,487 (33.7) | ||
West | 10,120 (16.1) | 88,864 (19.8) | 10,119 (16.1) | 88,876 (19.8) | ||
Unknown/Missing | 489 (0.8) | 4,476 (1.0) | 483 (0.8) | 4,514 (1.0) | ||
Employment status of primary policy holder, n (%) | ||||||
Employed | 12,346 (19.6) | 106,760 (23.8) | < 0.0001 | 19,104 (30.4) | 115,974 (25.8) | 0.003 |
Not Employed | 8,659 (13.8) | 61,918 (13.8) | 9,428 (15.0) | 54,941 (12.2) | ||
Unknown/missing | 41,888 (66.6) | 280,499 (62.4) | 34,361 (54.6) | 278,262 (61.9) | ||
Charlson Comorbidity Indexa, mean (SD) | 2.3 (1.7) | 0.4 (1.0) | < 0.0001 | 0.4 (0.9) | 0.4 (1.0) | < 0.0001 |
Number of unique medicationsb, mean (SD) | 7.5 (4.9) | 4.6 (4.6) | < 0.0001 | 4.3 (4.5) | 4.5 (4.6) | < 0.0001 |
Duration of follow up, mean (SD) months/median (interquartile range, IQR) | 25.4 (20.1)/19.3 (0.1–108.0) | 28.3 (20.0)/22.1 (1.7-108.1) | < 0.0001 | 32.1 (21.9)/25.9 (5.9–108.0) | 28.9 (20.5)/22.5 (4.9-108.1) | < 0.0001 |