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Table 4 Factors associated with a divergent second medical opinion by multivariate logistic regression analysis

From: Predictive factors of diagnostic and therapeutic divergence in a nationwide cohort of patients seeking second medical opinion

Characteristics OR 95 % CI P-value
Class of diseases
 Oncology and hematological diseases 1 (Ref) - -  
 Cardiovascular diseases 2.609 1.441 4.723 < 0.0001
 Reproductive diseases 1.746 0.923 3.303
 Skin disorders 1.356 0.483 3.808
 Digestive system diseases 1.759 0.867 3.570
 Endocrine and metabolic diseases 2.072 1.089 3.944
 Gynecological diseases 5.176 3.154 8.494
 Respiratory diseases 3.639 1.357 9.758
 Orthopedics and rhumatological diseases 1.266 0.860 1.864
 Nervous system and sensory organ diseases 1.267 0.761 2.11
 Urological diseases 4.246 2.053 8.782
Complexity
 Normal or common 1 (Ref) - - < 0.0001
 Specific/exceptional 2.784 2.157 3.592
Time required for file review 0.985 0.959 1.011 0.26
Region of residence
 Ile-de-France 1 (Ref) - - 0.18
 Auvergne-Rhône-Alpes, Bourgogne-Franche-Comte 1.044 0.680 1.601
 Bretagne, Normandie, Pays de la Loire, Centre-Val de Loire 1.64 1.121 2.399
 Hauts-de-France, Grand Est 1.125 0.784 1.613
 Nouvelle-Aquitaine 0.98 0.583 1.647
 PACA, Occitanie 1.209 0.817 1.79
Professional status
 Intermediate profession 1 (Ref) - - 0.39
 Self-employed, business owner or manager 0.78 0.563 1.082
 Other 0.915 0.557 1.502
 Currently unemployed (job seekers or students) 0.813 0.499 1.323
 Manual labourer 0.944 0.449 1.983
 Retired 1.291 0.743 2.244
Age category
 Adult (36 to 50 years) 1 (Ref) - - 0.40
 Adult (19 to 35 years) 1.219 0.892 1.666  
 Adult (51 to 65 years) 0.949 0.658 1.368  
 Child (< 18 years) 1.211 0.654 2.24  
 Older adult (66 to 80 years) 0.705 0.410 1.211  
 Older adult (81 to 95 years) 0.573 0.185 1.771  
 Sex Male (Ref = Female) 1.25 0.955 1.637 0.10