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Table 2 Healthcare resource utilization and annual costs during the baseline period

From: Incremental burden of comorbid major depressive disorder in patients with type 2 diabetes or cardiovascular disease: a retrospective claims analysis

 

Patients with T2D

Patients with CVD

 

With comorbid MDD

(n = 11,446)

Without comorbid MDD

(n = 11,446)

P value

With comorbid MDD

(n = 14,149)

Without comorbid MDD

(n = 14,149)

P value

Baseline average duration of analysis, months

 Mean (SD)

 

43.1 (28.9)

43.1 (28.0)

0.99

42.8 (29.8)

43.4 (29.6)

0.11

All-cause healthcare resource utilization during the baseline period, n (%)

 Proportion of patients requiring:

  Hospitalizations

 

1222 (10.7)

872 (7.6)

< 0.0001

2250 (15.9)

1606 (11.4)

< 0.0001

  ED visits

 

4368 (38.2)

3890 (34.0)

< 0.0001

7121 (50.3)

6431 (45.5)

< 0.0001

  Outpatient visits

 

10,777 (94.2)

10,606 (92.7)

< 0.0001

13,887 (98.1)

13,786 (97.4)

< 0.0001

Annual all-cause costs during the baseline period, $

 Pharmacy

  Mean (SD)

 

1859 (6203)

1206 (4265)

< 0.0001

2498 (6931)

1775 (7679)

< 0.0001

 Medical

  Mean (SD)

 

6127 (20,069)

4484 (15,874)

< 0.0001

8112 (22,857)

6335 (23,142)

< 0.0001

 Total

  Mean (SD)

 

7986 (22,158)

5689 (17,467)

< 0.0001

10,610 (25,425)

8110 (25,077)

< 0.0001

  1. Statistical differences were assessed using t tests. Significant P values (< 0.05) are shown in bold italic.
  2. CVD cardiovascular disease, ED emergency department, MDD major depressive disorder, SD standard deviation, T2D type 2 diabetes